A Green Approach for the Synthesis of 1, 4‐Diphenylbutadiyne‐1, 3 via C−H Activated Aerobic Csp−Csp Homocoupling Catalyzed by CuFe2O4 Nanoparticles. Issue 12 (21st March 2023) - Raigar, Ashok K.
Abstract: An inexpensive, simple, and greener catalytic system with lower toxicity using CuFe2 O4 nanoparticles in the presence of piperidine and dry toluene as a solvent has been reported for the synthesis of 1, 4‐diphenylbutadiyne‐1, 3, via C−H activated aerobic Csp −Csp homocoupling. This protocol provides 66 % of yield at the gram‐scale level making it appropriate for production at a larger scale. The catalyst shows reusability for up to five cycles without losing any significant catalytic activity. Abstract : Synthesis of 1, 4‐diphenylbutadiyne‐1, 3, via C−H activated aerobic Csp −Csp homocoupling under mild aerobic reaction conditions using 10 mol % of CuFe2 O4 MNPs in dry toluene at 90 °C in the presence of piperidine as an additive.