Establishing Clinical Cut-points on the Pediatric PROMIS-Pain Interference Scale in Youth With Abdominal Pain. Issue 3 (March 2022)

• Record Type: Journal Article
• Authors: Gamwell, Kaitlyn L.; Mara, Constance A.; Hommel, Kevin A.; Kashikar-Zuck, Susmita; Cunningham, Natoshia R.
• Is Part Of: Clinical journal of pain. Volume 38:Issue 3(2022)
• Publication Date: 2022-03
• Subjects: pediatric pain -- interference -- impairment -- PROMIS -- abdominal pain; Pain -- Periodicals; Pain -- Treatment -- Periodicals; Analgesia -- Periodicals; 616.047205
• DOI: 10.1097/AJP.0000000000001012
• Languages: English
• ISSNs: 0749-8047

Abstract

Abstract : Objective: Abdominal pain is a common presenting complaint in youth seeking medical care and can be debilitating. Therefore, it is important to understand the impact of pain on functioning using a clinically sensitive approach. The National Institutes of Health has established a common core of psychometrically precise measures through the Patient-Reported Outcomes Measurement Information System (PROMIS) initiative. The Pediatric PROMIS-Pain Interference (PPPI) scale was developed to measure pain-related interference, drawing from existing legacy measures. However, its clinical validity has not been thoroughly established in clinical populations. The current study sought to develop clinical cut-points and investigate the validity of the PPPI in a large sample (N=5281) of youth presenting to gastroenterological care with abdominal pain symptoms. Materials and Methods: Convergent validity of the PPPI was investigated. Quartile and tertile groupings of the PPPI were calculated and compared with cut-points derived from healthy populations and mixed convenience samples on clinical outcomes via multivariate analyses of variance. Results: There was good evidence of convergent validity. The tertile solution was superior in classifying different levels of pain-related outcomes as compared with other cut-points. The tertile solution suggested the following PPPI groupings: minimal (⩽51), moderate (52 to 59), and severe (≥60). Discussion: Results suggest the PPPI is a valid measure with clinically meaningful cut-points to assess pain-related interference in youth with abdominal pain.