Integrated Cardiopulmonary MRI Assessment of Pulmonary Hypertension. Issue 3 (5th August 2021)

• Record Type: Journal Article
• Authors: Saunders, Laura C.; Hughes, Paul J. C.; Alabed, Samer; Capener, David J.; Marshall, Helen; Vogel‐Claussen, Jens; van Beek, Edwin J. R.; Kiely, David G.; Swift, Andrew J.; Wild, Jim M.
• Is Part Of: Journal of magnetic resonance imaging. Volume 55:Issue 3(2022)
• Page Start: 633
• Page End: 652
• Publication Date: 2021-08-05
• Subjects: pulmonary hypertension -- cardiopulmonary -- cardiac -- pulmonary -- lung; Magnetic resonance imaging -- Periodicals; 616
• DOI: 10.1002/jmri.27849
• Languages: English
• ISSNs: 1053-1807

Abstract

Abstract : Pulmonary hypertension (PH) is a heterogeneous condition that can affect the lung parenchyma, pulmonary vasculature, and cardiac chambers. Accurate diagnosis often requires multiple complex assessments of the cardiac and pulmonary systems. MRI is able to comprehensively assess cardiac structure and function, as well as lung parenchymal, pulmonary vascular, and functional lung changes. Therefore, MRI has the potential to provide an integrated functional and structural assessment of the cardiopulmonary system in a single exam. Cardiac MRI is used in the assessment of PH in most large PH centers, whereas lung MRI is an emerging technique in patients with PH. This article reviews the current literature on cardiopulmonary MRI in PH, including cine MRI, black‐blood imaging, late gadolinium enhancement, T1 mapping, myocardial strain analysis, contrast‐enhanced perfusion imaging and contrast‐enhanced MR angiography, and hyperpolarized gas functional lung imaging. This article also highlights recent developments in this field and areas of interest for future research including cardiac MRI‐based diagnostic models, machine learning in cardiac MRI, oxygen‐enhanced 1 H imaging, contrast‐free 1 H perfusion and ventilation imaging, contrast‐free angiography and UTE imaging. Evidence Level: 5 Technical Efficacy: Stage 3