Decreased plasma motilin concentrations in pregnancy. Issue 6353 (20th November 1982)

• Record Type: Journal Article
• Authors: Christofides, N D; Ghatei, M A; Bloom, S R; Borberg, C; Gillmer, M D
• Is Part Of: BMJ. Volume 285:Issue 6353(1982)
• Page Start: 1453
• Page End: 1454
• Publication Date: 1982-11-20
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.285.6353.1453
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : Plasma motilin concentrations were measured in 37 women during the second and third trimester of pregnancy and one week after delivery. The mean plasma motilin concentrations, both fasting and after a glucose load and a mixed meal, were significantly (p less than 0.001) reduced during pregnancy, returning to the normal range one week post partum. Pregnancy appears to have a profound inhibitory effect on plasma motilin, and this may in part be responsible for the gastrointestinal hypomotility associated with pregnancy.