AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection. Issue 2 (4th December 2021)

• Record Type: Journal Article
• Authors: Spinicci, Michele; Mazzoni, Alessio; Borchi, Beatrice; Graziani, Lucia; Mazzetti, Marcello; Bartalesi, Filippo; Botta, Annarita; Tilli, Marta; Pieralli, Filippo; Coppi, Marco; Giovacchini, Nicla; Colao, Maria Grazia; Saccardi, Riccardo; Rossolini, Gian Maria; Annunziato, Francesco; Bartoloni, Alessandro
• Is Part Of: European journal of immunology. Volume 52:Issue 2(2022)
• Page Start: 352
• Page End: 355
• Publication Date: 2021-12-04
• Subjects: COVID‐19 -- HIV -- CD4 -- immunocompromised -- monoclonal -- convalescent plasma; Immunology -- Periodicals; 616.079
• DOI: 10.1002/eji.202149574
• Languages: English
• ISSNs: 0014-2980

Abstract

Abstract : A late presenter AIDS patient with severe T cell depletion presented non‐severe COVID‐19 symptoms, with prolonged viral shedding. Our case report supports the hypothesis that an effective T cell response may be dispensable for the control of COVID‐19 progression to severe forms, while it may be necessary for SARS‐CoV‐2 clearance.