Liposomal ferric pyrophosphate and ascorbic acid supplementation in pregnant women with iron deficiency anaemia: haematochemical, obstetric, neonatal and psychological outcomes in a prospective observational study. (17th February 2022)

• Record Type: Journal Article
• Authors: Vitale, Salvatore Giovanni; Fiore, Maria; La Rosa, Valentina Lucia; Rapisarda, Agnese Maria Chiara; Mazza, Gabriele; Paratore, Marco; Commodari, Elena; Caruso, Salvatore
• Is Part Of: International journal of food sciences and nutrition. Volume 73:Number 2(2022)
• Page Start: 221
• Page End: 229
• Publication Date: 2022-02-17
• Subjects: Liposomal iron -- microencapsulated -- micronized -- iron deficiency -- anaemia -- pregnancy; Food -- Analysis -- Periodicals; Nutrition -- Periodicals; 641.3
• DOI: 10.1080/09637486.2021.1950129
• Languages: English
• ISSNs: 0963-7486

Abstract

Abstract: This study aimed to determine the effects of liposomal iron pyrophosphate/ascorbic acid on clinical and psychological outcomes in pregnant women. Women at the 11th–13th weeks of gestation with iron deficiency anaemia assuming Sideremil™ from April 2018 to May 2019 were recruited. Haematochemical, obstetric, neonatal and psychological outcomes were investigated at the enrolment, 21–23 weeks of gestation, 30–32 weeks of gestation and after 6 weeks from childbirth. Results showed significant positive effects on haemoglobin, ferritin, sideremia and transferrin levels, compared to baseline data. A significant improvement of anxiety and depression levels was also observed. Regarding the quality of life, all the domains significantly improved, especially the Physical Role domain. Our results indicate that Sideremil ™ may be a valid treatment for iron deficiency anaemia in pregnant women, since it significantly improves haematological and mental health outcomes. However, further studies are needed to confirm these results.