Phenolic acids and flavonoids from Salvia plebeia and HPLC-UV profiling of four Salvia species. Issue 3 (March 2022)

• Record Type: Journal Article
• Authors: Paje, Leo Adrianne; Choi, Jungwon; Lee, Hak-Dong; Kim, Juree; Yu, A Ram; Bae, Min-Jung; Geraldino, Paul John L.; Lee, Sanghyun
• Is Part Of: Heliyon. Volume 8:Issue 3(2022)
• Publication Date: 2022-03
• Subjects: Salvia plebeia -- Open column chromatography -- 6-hydroxyluteolin 7-O-glucoside -- Rosmarinic acid -- HPLC-UV analysis; Research -- Periodicals; Medical sciences -- Periodicals; Natural history -- Periodicals; Social sciences -- Periodicals; Earth sciences -- Periodicals; Physical sciences -- Periodicals; 507.2
• DOI: 10.1016/j.heliyon.2022.e09046
• Languages: English
• ISSNs: 2405-8440

Abstract

Abstract: We isolated and purified phenolic acids and flavonoids from the ethanolic extract of Salvia plebeia using silica gel and a Sephadex LH-20 column chromatography. Spectroscopy revealed the isolated compounds were caffeic acid, rosmarinic acid, hispidulin, luteolin, jaceosidin, nepitrin, homoplantaginin, 6-hydroxyluteolin 7- O -glucoside, 6-methoxynaringenin 7- O -glucoside, naasanone, and cosmosiin. Quantitative analyses, using high-performance liquid chromatography coupled with UV (HPLC-UV), revealed that the major flavonoid from S. plebeia was 6-hydroxyluteolin 7- O -glucoside (100.63 mg/g) and the most abundant phenolic acid was rosmarinic acid (47.73 mg/g). Furthermore, among four other Salvia species, S. officinalis contained the highest overall phenolic acid and flavonoid level but these were still lower than S. plebeia . These results can help assess the potential of phenolic acids and flavonoids as potent sources of pharmacological ingredients from different Salvia species extracts. Abstract : Salvia plebeia ; Open column chromatography; 6-hydroxyluteolin 7- O -glucoside; Rosmarinic acid; HPLC-UV analysis.