A relation between high-density-lipoprotein cholesterol and bile cholesterol saturation. Issue 6303 (21st November 1981)

• Record Type: Journal Article
• Authors: Thornton, J R; Heaton, K W; Macfarlane, D G
• Is Part Of: BMJ. Volume 283:Issue 6303(1981)
• Page Start: 1352
• Page End: 1354
• Publication Date: 1981-11-21
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.283.6303.1352
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : The association of cholesterol gall stones with coronary artery disease is controversial. To investigate this possible relation at the biochemical level, bile cholesterol saturation and the plasma concentrations of triglycerides, total cholesterol, and high-density-lipoprotein cholesterol (HDL cholesterol) were measured in 25 healthy, middle-aged women. Bile cholesterol saturation index was negatively correlated with HDL cholesterol. It was positively correlated with plasma triglycerides and with total cholesterol minus HDL cholesterol. These findings provide a biochemical basis for a positive association in women between cholesterol gall stones and coronary artery disease.