Effects of Progestogen Oral Contraception with Norethisterone on Blood Clotting and Platelets. Issue 5837 (18th November 1972)

• Record Type: Journal Article
• Authors: Poller, L.; Thomson, Jean M.; Thomas, P. W.
• Is Part Of: BMJ. Volume 4:Issue 5837(1972)
• Page Start: 391
• Page End: 393
• Publication Date: 1972-11-18
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.4.5837.391
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : The effects on clotting tests and platelet function of six months' continuous administration of the 19-norsteroid, progestogen-only contraceptive, norethisterone, have been studied in four groups of women. In a group of women who have not previously taken oral contraceptive no acceleration of clotting or platelet factors was found, but in contrast a tendency to reduced coagulability was observed. Women who had previously been taking combined oestrogen-progestogen preparations showed reduced clotting and platelet parameters when norethisterone was substituted. No changes in clotting or platelets were found in women who changed from 17-acetoxysteroid progestogen chloramadinone acetate or in a group of women started postpartum.