Antimicrobial limonoids from the seeds of Cipadessa cinerascensa. Issue 3 (4th March 2022)

• Record Type: Journal Article
• Authors: Tong, Ya-Nan; Guo, Jia; Chen, Yu-Feng; Zhang, Guo-Xu
• Is Part Of: Journal of Asian natural products research. Volume 24:Issue 3(2022)
• Page Start: 238
• Page End: 244
• Publication Date: 2022-03-04
• Subjects: Cipadessa cinerascensa -- Meliaceae -- limonoids -- antimicrobial activity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2021.1915996
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Phytochemical investigation on the 90% EtOH extract of the seeds of Cipadessa cinerascensa led to the isolation of three new limonoids, cinerascenoids A-C (1-3 ). Structural elucidation of all the compounds were performed by spectral methods such as 1 D and 2 D ( 1 H - 1 H COSY, HMQC, and HMBC) NMR spectroscopy. All the limonoids were in vitro evaluated for their antimicrobial activities against six pathogenic microorganisms. Limonoids 1 and 2 exhibited some activities against three Gram negative bacteria with MIC values less than 60 μg/ml. Graphical Abstract: UF0001