Nucleic Acid Integrated Technologies for Electrochemical Point‐of‐Care Diagnostics: A Comprehensive Review. Issue 2 (6th September 2021)

• Record Type: Journal Article
• Authors: Surucu, Ozge; Öztürk, Elif; Kuralay, Filiz
• Is Part Of: Electroanalysis. Volume 34:Issue 2(2022)
• Page Start: 148
• Page End: 160
• Publication Date: 2021-09-06
• Subjects: Point-of-care testing -- healthcare -- nucleic acids -- electrochemistry; Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.202100309
• Languages: English
• ISSNs: 1040-0397

Abstract

Abstract: The need for routine and immediate healthcare monitoring has inspired "near‐patient testing" or in other words "point‐of‐care testing (POCT)". Therefore, POCT can be defined as laboratory tests that are performed at the patient's bedside or in the immediate vicinity of the incident. Among many POCTs, nucleic acid‐based testing has attracted enormous attention for the diagnosis of important genetic, inherited and infectious diseases such as cancer and coronavirus. In this review, we outline the integration of nucleic acids into the remarkable electrochemical point‐of‐care diagnostics including microfluidic, paper and smartphone‐based approaches, CRISPR/Cas and liquid biopsy related systems and DNA damage monitoring. Abstract :