Right ventricular ST‐elevation myocardial infarction as a cause of death in idiopathic pulmonary arterial hypertension. (1st April 2017)

• Record Type: Journal Article
• Authors: Zhan, Yang; Burstein, Barry; Abualsaud, Ali O.; Nosair, Mohamed; Hirsch, Andrew M.; Lesenko, Lyda; Langleben, David
• Is Part Of: Pulmonary circulation. Volume 7:Number 2(2017)
• Page Start: 555
• Page End: 558
• Publication Date: 2017-04-01
• Subjects: coronary artery disease -- myocardial infarction -- pulmonary arterial hypertension -- right ventricle -- vasodilators; Pulmonary circulation -- Periodicals; Pulmonary circulation; Electronic journals -- Sciences; Periodicals; 616.24005
• DOI: 10.1177/2045893217704435
• Languages: English
• ISSNs: 2045-8932

Abstract

Abstract : A 32‐year‐old woman with advanced idiopathic pulmonary arterial hypertension (PAH), treated with oral tadalafil and intravenous epoprostenol, presented with typical angina pectoris of one day's duration. Her electrocardiogram, previously typical of pulmonary hypertension, revealed an acute ST‐elevation myocardial infarction in the anterior precordial leads. She had a prior coronary angiogram, in preparation for lung transplantation, that revealed normal coronary arteries. Urgent coronary angiography showed acute occlusion of several acute marginal coronary branches that feed the right ventricle (RV). Coronary angioplasty and stenting was unable to adequately restore coronary perfusion. Despite support, she developed progressive cardiogenic shock and died three days later. This is an unusual complication of PAH.