Chemocatalytic value addition of glucose without carbon–carbon bond cleavage/formation reactions: an overview. Issue 8 (9th February 2022)

• Record Type: Journal Article
• Authors: Dutta, Saikat; Bhat, Navya Subray
• Is Part Of: RSC advances. Volume 12:Issue 8(2022)
• Page Start: 4891
• Page End: 4912
• Publication Date: 2022-02-09
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d1ra09196d
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Recent advances on the production and applications of major C6 products from glucose have been reported in this review. The preparation and derivative chemistry of sorbitol, sorbitan, 5-(hydroxymethyl)furfural, and isosorbide have been elaborated. Abstract : As the monomeric unit of the abundant biopolymer cellulose, glucose is considered a sustainable feedstock for producing carbon-based transportation fuels, chemicals, and polymers. The chemocatalytic value addition of glucose can be broadly classified into those involving C–C bond cleavage/formation reactions and those without. The C6 products obtained from glucose are particularly satisfying because their syntheses enjoy a 100% carbon economy. Although multiple derivatives of glucose retaining all six carbon atoms in their moiety are well-documented, they are somewhat dispersed in the literature and never delineated coherently from the perspective of their carbon skeleton. The glucose-derived chemical intermediates discussed in this review include polyols like sorbitol and sorbitan, diols like isosorbide, furanic compounds like 5-(hydroxymethyl)furfural, and carboxylic acids like gluconic acid. Recent advances in producing the intermediates mentioned above from glucose following chemocatalytic routes have been elaborated, and their derivative chemistry highlighted. This review aims to comprehensively understand the prospects and challenges associated with the catalytic synthesis of C6 molecules from glucose.