Synthesis of acridinones via palladium-catalyzed reductive annulation of 2-nitrobenzaldehydes and resorcinols. Issue 4 (7th January 2022)

• Record Type: Journal Article
• Authors: Xie, Rong; Mao, Wenhui; Jia, Huanhuan; Lu, Guangpeng; Sun, Jialu; Jiang, Huanfeng; Zhao, He; Zhang, Min
• Is Part Of: Organic chemistry frontiers. Volume 9:Issue 4(2022)
• Page Start: 953
• Page End: 958
• Publication Date: 2022-01-07
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d1qo01693h
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : Through a palladium-catalyzed reductive annulation reaction of resorcinols and 2-nitrobenzaldehydes, reported is a new synthesis of acridinones with the features of operational simplicity, broad substrate scope, and readily available feedstocks. Abstract : The catalytic conversion of biomass-derived feedstocks into functional molecules is of significance to synthetic organic chemistry. Herein, through a palladium-catalyzed reductive annulation reaction of resorcinols and 2-nitrobenzaldehydes, we present a new approach for the direct synthesis of acridinone derivatives, featuring operational simplicity, good substrate compatibility, and readily available feedstocks.