Variation in Peritoneal Dialysis Time on Therapy by Country: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study. Issue 6 (June 2022)

• Record Type: Journal Article
• Authors: Lambie, Mark; Zhao, Junhui; McCullough, Keith; Davies, Simon J.; Kawanishi, Hideki; Johnson, David W.; Sloand, James A.; Sanabria, Mauricio; Kanjanabuch, Talerngsak; Kim, Yong-Lim; Shen, Jenny I.; Pisoni, Ronald L.; Robinson, Bruce M.; Perl, Jeffrey
• Other Names: author non-byline.; Johnson David author non-byline.; Perl Jeffrey author non-byline.; Kawanishi Hideki author non-byline.; Kim Yong-Lim author non-byline.; Kanjanabuch Talerngsak author non-byline.; Davies Simon author non-byline.; Bernardo Angelito author non-byline.; Pisoni Ron author non-byline.; Robinson Bruce author non-byline.; Shen Jenny author non-byline.; Badve Sunil author non-byline.; Boudville Neil author non-byline.; Brown Fiona author non-byline.; Chow Josephine author non-byline.; Collins John author non-byline.; Morton Rachael author non-byline.; Wilson Scott author non-byline.; Vychytil Andreas author non-byline.; Van Biesen Wim author non-byline.; Figueiredo Ana author non-byline.; de Moraes Thyago author non-byline.; Brunier Gillian author non-byline.; Jain Arsh author non-byline.; Jassal Vanita author non-byline.; Nessim Sharon author non-byline.; Oliver Matthew author non-byline.; Price Valerie author non-byline.; Quinn Rob author non-byline.; Fang Wei author non-byline.; Szeto CC author non-byline.; Wang Angela author non-byline.; Fukasawa Mizuya author non-byline.; Ito Yasuhiko author non-byline.; Ryuzaki Munekazu author non-byline.; Tomo Tadashi author non-byline.; Manzano Alfonso Cueto author non-byline.; Marshall Mark author non-byline.; Ljungman Susanne author non-byline.; Boongird Sarinya author non-byline.; Boonyakrai Chanchana author non-byline.; Cheawchanwattana Areewan author non-byline.; Halue Guttiga author non-byline.; Sritippayawan Suchai author non-byline.; Tatiyanupanwong Sajja author non-byline.; Tungsanga Kriang author non-byline.; Bowes Elaine author non-byline.; Brown Edwina author non-byline.; Fluck Richard author non-byline.; Goh Bak Leong author non-byline.; Hurst Helen author non-byline.; Wilkie Martin author non-byline.; Woodrow Graham author non-byline.; Bender Filitsa author non-byline.; Bernardini Judith author non-byline.; Chatoth Dinesh author non-byline.; Crabtree John author non-byline.; Finkelstein Fred author non-byline.; Ghaffari Arshia author non-byline.; Mehrotra Rajnish author non-byline.; Piraino Beth author non-byline.; Schreiber Martin author non-byline.; Teitelbaum Isaac author non-byline.;
• Is Part Of: Clinical journal of the American Society of Nephrology. Volume 17:Issue 6(2022)
• Page Start: 861
• Page End: 871
• Publication Date: 2022-06
• Subjects: peritoneal dialysis -- hemodialysis -- kidney transplantation
• DOI: 10.2215/CJN.16341221
• Languages: English
• ISSNs: 1555-9041

Abstract

Visual Abstract: Abstract : Background and objectives: Quantifying contemporary peritoneal dialysis time on therapy is important for patients and providers. We describe time on peritoneal dialysis in the context of outcomes of hemodialysis transfer, death, and kidney transplantation on the basis of the multinational, observational Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) from 2014 to 2017. Design, setting, participants, & measurements: Among 218 randomly selected peritoneal dialysis facilities (7121 patients) in the PDOPPS from Australia/New Zealand, Canada, Japan, Thailand, the United Kingdom, and the United States, we calculated the cumulative incidence from peritoneal dialysis start to hemodialysis transfer, death, or kidney transplantation over 5 years and adjusted hazard ratios for patient and facility factors associated with death and hemodialysis transfer. Results: Median time on peritoneal dialysis ranged from 1.7 (interquartile range, 0.8–2.9; the United Kingdom) to 3.2 (interquartile range, 1.5–6.0; Japan) years and was longer with lower kidney transplantation rates (range: 32% [the United Kingdom] to 2% [Japan and Thailand] over 3 years). Adjusted hemodialysis transfer risk was lowest in Thailand, but death risk was higher in Thailand and the United States compared with most countries. Infection was the leading cause of hemodialysis transfer, with higher hemodialysis transfer risks seen in patients having psychiatric disorder history or elevated body mass index. The proportion of patients with total weekly Kt/V ≥1.7 at a facility was not associated with death or hemodialysis transfer. Conclusions: Countries in the PDOPPS with higher rates of kidney transplantation tended to have shorter median times on peritoneal dialysis. Identification of infection as a leading cause of hemodialysis transfer and patient and facility factors associated with the risk of hemodialysis transfer can facilitate interventions to reduce these events. Podcast: This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2022_05_31_CJN16341221.mp3