The Effect of Exercise on Lipid Profiles and Inflammatory Markers in Lean Male Adolescents: A Prospective Interventional Study. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Huang, Chun-Jui; Kwok, Chin-Fai; Chou, Chung-Hsing; Chou, Yu-Ching; Ho, Low-Tone; Shih, Kuang-Chung
• Is Part Of: Journal of investigative medicine. Volume 63:Issue 1(2015:Jan.)
• Page Start: 29
• Page End: 34
• Publication Date: 2015-01
• Subjects: adiponectin -- inflammatory cytokines -- exercise -- adolescent; Clinical medicine -- Periodicals; Medicine -- Research -- Periodicals; Medicine; Research -- United States; Clinical medicine; Medicine -- Research; Periodicals; 616.075
• DOI: 10.1097/JIM.0000000000000120
• Languages: English
• ISSNs: 1081-5589

Abstract

Background: Physical activity improves body composition and inflammatory markers in obese individuals, but little is known about the nonobese population. Objective: The aim of this study was to investigate associations between exercise and inflammatory cytokines in lean male adolescents in Taiwan. Methods: This interventional study enrolled a total of 79 normal body weight male adolescents [mean age, 16.8 (1.0) years] from the Army Academy of Taiwan. Body composition and inflammatory markers were measured at baseline and upon completion of a 12-week exercise intervention program. Results: Subjects' postintervention anthropometric measures, including waist circumference [74.6 (5.2) → 72.6 (5.2) cm], hip circumference [92.3 (4.1) → 89.9 (5.0) cm], body fat mass [10.2 (3.2) → 8.2 (3.2) kg], and body fat percentage [15.8% (4.2) → 12.6 (4.5)%] declined significantly compared to preintervention (all P < 0.001), as did systolic blood pressure ( P = 0.002) and mean blood pressure ( P = 0.020). Postintervention body height and free fat mass increased significantly (both P < 0.001). Subjects' postintervention lipids including total cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides increased significantly (all P < 0.001). Inflammatory markers including adiponectin [14.32 (6.68) → 31.31 (30.53) μg/mL, P < 0.001], interleukin 6 [2.15 (4.81) → 2.86 (6.37) pg/mL, P = 0.005], and C-reactive protein [1.00 (2.57) → 2.30 (4.17) μg/mL, P < 0.001] increased significantly postintervention, but not leptin. Conclusions: Exercise training significantly improves body composition and anti-inflammatory adiponectin levels in lean male adolescents.