Effect of Intra-amniotic Oestriol Sulphate on Uterine Contractions. Issue 5660 (28th June 1969)

• Record Type: Journal Article
• Authors: Klopper, A. I.; Dennis, K. J.; Farr, Valerie
• Is Part Of: BMJ. Volume 2:Issue 5660(1969)
• Page Start: 786
• Page End: 789
• Publication Date: 1969-06-28
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.2.5660.786
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : The effects of oestriol sulphate on myometrial activity in a group of young primigravidae, who were at 41 or more weeks' gestation, are compared with those of a placebo in a double-blind trial. Both compounds were administered over a period of six hours directly into the uterine cavity following artificial rupture of membranes. Intra-amniotic pressure recordings demonstrated a peak in the mean intensity in uterine contractions in the oestriol-treated and placebo-treated groups at six and four hours, respectively. The length of labour tended to be shorter in those patients having greater uterine activity.