The efficacy of the use of heparin in the emergency room in patients with acute ST-segment elevation myocardial infarction. Issue 1 (March 2022)

• Record Type: Journal Article
• Authors: Zuo, Guoxing; Li, Ying; Hu, Sheng; Wang, Kuan; Zhao, Hui; Wang, Dong; Qian, Xiaoqian; Du, Xinping
• Is Part Of: Journal of Radiation Research and Applied Sciences. Volume 15:Issue 1(2022)
• Page Start: 187
• Page End: 192
• Publication Date: 2022-03
• Subjects: Thrombolysis in myocardial infarction score -- Myocardial infarction -- Adverse event -- Coronary artery revascularization -- STEMI -- Heparin; Ionizing radiation -- Periodicals; Nuclear physics -- Periodicals; Radiation; Radiation; Periodicals; 539.7
• DOI: 10.1016/j.jrras.2022.03.002
• Languages: English
• ISSNs: 1687-8507

Abstract

Abstract: Aim: To investigate the efficacy of the use of heparin in the emergency room in patients with acute ST-segment elevation myocardial infarction (STEMI). Methods: 200 STEMI patients undergoing primary percutaneous coronary intervention (PCI) were randomly divided into the research and control groups (heparin administration in emergency room and catheterization laboratory, respectively). Results: The rate of thrombolysis in myocardial infarction (TIMI) grade 2 flow in the research participants was significantly higher than that in the controls ( P < 0.05). The stent diameter in the research patients was smaller than that in the control participants ( P < 0.05); while the stent length in the research patients was shorter than that in the controls ( P < 0.05). The slow flow rate in the research patients was similar to that in the control participants ( P > 0.05). There were no differences between the groups in the corrected TIMI frame counts or intraoperative complications ( P > 0.05). The ST-segment resolution rate within 2 h post-PCI was 90.0% in the research patients and 83.8% in the controls ( P > 0.05). There was no significant difference in the cardiac troponin and N terminal prohormone of brain natriuretic peptide (NT-proBNP) levels between the two groups post-PCI ( P > 0.05). The left ventricular end-diastolic volume and left ventricular ejection fraction (LVEF) during hospitalization were similar between the groups ( P > 0.05). Conclusion: Administering heparin to STEMI patients in the emergency room can increase the rate of coronary artery revascularization.