ARFI elastography of the omentum: feasibility and diagnostic performance in differentiating benign from malignant omental masses. Issue 1 (6th May 2022)

• Record Type: Journal Article
• Authors: Alhyari, Amjad; Görg, Christian; Dietrich, Christoph Frank; Trenker, Corrina; Strauch, Lena; Safai Zadeh, Ehsan
• Is Part Of: BMJ open gastroenterology. Volume 9:Issue 1(2022)
• Publication Date: 2022-05-06
• Subjects: GASTROINTESTINAL ULTRASOUND -- IMAGING -- RADIOLOGY -- SURGICAL ONCOLOGY -- TUMOUR MARKERS; Gastroenterology -- Periodicals; 616.33005
• DOI: 10.1136/bmjgast-2022-000901
• Languages: English
• ISSNs: 2054-4774

Abstract

Abstract : Objective: To evaluate the feasibility and diagnostic performance of acoustic radiation force impulse (ARFI) elastography in different omental masses (OM). Design: This was a retrospective analysis of 106 patients with OM defined as omental thickness ≥1 cm, who underwent abdominal B-mode ultrasound (US) and standardised ARFI examinations of the OM between September 2018 and June 2021 at our university hospital. A cytohistological confirmation was available in 91/106 (85.8%) of all OM, including all 65/65 (100%) malignant OM (mOM) and 26/41 (63.4%) of benign OM (bOM). In 15/41 (36.6%) of bOM; cross-sectional imaging and or US follow-up with a mean duration of 19.8±3.1 months was performed. To examine the mean ARFI velocities (MAV) for potential cut-off values between bOM and mOM a receiver operating characteristic analysis was implemented. Results: The MAV in the mOM group (2.71±1.04 m/s) was significantly higher than that of bOM group (1.27±0.87 m/s) (p<0.001). Using 1.97 m/s as a cut-off yielded a sensitivity and specificity of 76.9% and 85.4%, respectively, in diagnosing mOM (area under the curve=0.851, 95% CI=0.774 to 0.928). Conclusion: ARFI elastography is feasible in the omentum and may represent a good non-invasive additional tool in differentiating bOM from mOM.