Parent-reported health status of preterm survivors in a Canadian cohort. Issue 1 (23rd June 2021)

• Record Type: Journal Article
• Authors: Ghotra, Satvinder; Feeny, David; Barr, Ronald; Yang, Junmin; Saigal, Saroj; Vincer, Michael; Afifi, Jehier; Shah, Prakeshkumar S; Lee, Shoo K; Synnes, Anne R
• Other Names: author non-byline.; Shah Prakesh S author non-byline.; Beltempo Marc author non-byline.; Toye Jennifer author non-byline.; Bodani Jaya author non-byline.; Seshia Mary author non-byline.; Alvaro Ruben author non-byline.; Silva Orlando Da author non-byline.; Barrington Keith author non-byline.; Drolet Christine author non-byline.; Claveau Martine author non-byline.; Ojah Cecil author non-byline.; Lee Shoo K author non-byline.; Zwicker Jill author non-byline.; Reichert Amber author non-byline.; Bodani Jaya author non-byline.; Moddemann Diane author non-byline.; Coughlin Kevin author non-byline.; Kelly Edmond author non-byline.; Banihani Rudaina author non-byline.; Khairy May author non-byline.; Dorval Veronique author non-byline.; Bélanger Sylvie author non-byline.; Monterrosa Luis author non-byline.
• Is Part Of: Archives of disease in childhood. Volume 107:Issue 1(2022)
• Page Start: 87
• Page End: 93
• Publication Date: 2021-06-23
• Subjects: neonatology -- epidemiology; Infants -- Diseases -- Periodicals; Newborn infants -- Diseases -- Periodicals; Fetus -- Diseases -- Periodicals; 618.920105
• DOI: 10.1136/archdischild-2021-321635
• Languages: English
• ISSNs: 1359-2998

Abstract

Abstract : Objectives: Health status (HS)/ health-related quality of life measures, completed by self or proxy, are important outcome indicators. Most HS literature on children born preterm includes adolescents and adults with limited data at preschool age. This study aimed to describe parent-reported HS in a large national cohort of extreme preterm children at preschool age and to identify clinical and sociodemographic variables associated with HS. Methods: Infants born before 29 weeks' gestation between 2009 and 2011 were enrolled in a prospective longitudinal national cohort study through the Canadian Neonatal Network (CNN) and the Canadian Neonatal Follow-Up Network (CNFUN). HS, at 36 months' corrected age (CA), was measured with the Health Status Classification System for Pre-School Children tool completed by parents. Information about HS predictors was extracted from the CNN and CNFUN databases. Results: Of 811 children included, there were 79, 309 and 423 participants in 23–24, 25–26 and 27–28 weeks' gestational age groups, respectively. At 36 months' CA, 78% had a parent-reported health concern, mild in >50% and severe in 7%. Most affected HS attributes were speech (52.1%) and self-care (41.4%). Independent predictors of HS included substance use during pregnancy, infant male sex, Score for Neonatal Acute Physiology-II, bronchopulmonary dysplasia, severe retinopathy of prematurity, caregiver employment and single caregiver. Conclusion: Most parents expressed no or mild health concerns for their children at 36 months' CA. Factors associated with health concerns included initial severity of illness, complications of prematurity and social factors.