Stepping it up: Physical activity is associated with a lower incidence of prolonged gastric transit time in capsule endoscopy. Issue 3 (29th November 2022)

• Record Type: Journal Article
• Authors: Macedo Silva, Vítor; Lima Capela, Tiago; Freitas, Marta; Arieira, Cátia; Xavier, Sofia; Boal Carvalho, Pedro; Rosa, Bruno; Moreira, Maria João; Cotter, José
• Is Part Of: Journal of gastroenterology and hepatology. Volume 38:Issue 3(2023)
• Page Start: 404
• Page End: 409
• Publication Date: 2022-11-29
• Subjects: capsule endoscopy -- physical activity -- prolonged gastric transit time -- quality in capsule endoscopy; Gastroenterology -- Periodicals; Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Liver Diseases -- Periodicals; 616.33
• DOI: 10.1111/jgh.16074
• Languages: English
• ISSNs: 0815-9319

Abstract

Abstract: Background and Aim: Physical activity has been proposed as a potential factor influencing capsule endoscopy (CE) gastric transit time (GTT). However, there is no reported factual evidence confirming this association. We aimed to prospectively assess the effect of physical activity in the first hour of CE in the occurrence of prolonged GTT. Methods: This is a prospective study including consecutive patients undergoing CE. For each patient, a step counter was attached to the CE register. The number of steps during the first hour of the procedure was registered. The main outcome was prolonged GTT (CE remaining in the stomach for > 1 h). Outcomes were adjusted for possible confounders by multivariate analysis. Results: We included 100 patients, 60% undergoing small bowel CE and 40% colon CE. The mean number of steps in the first hour was significantly lower in patients with prolonged GTT (2009 ± 1578 steps) comparatively with those without prolonged GTT (3597 ± 1889 steps) ( P < 0.001). On multivariate analysis including significant confounders, steps in the first hour were an independent predictor of prolonged GTT ( P = 0.018). Single‐handedly, the number of steps taken in the first hour had a good acuity for predicting prolonged GTT (area under the curve = 0.74; P < 0.001), with an optimal cut‐off of 2000 steps (sensitivity 81.3% and specificity 70%). Conclusions: Physical activity during the first hour of CE significantly decreased the occurrence of prolonged GTT. These findings pave the way for further definition of clear instructions to give to patients undergoing CE.