Antihypertensive treatment changes and related clinical outcomes in older hospitalized patients. (21st December 2022)

• Record Type: Journal Article
• Authors: Cicco, Sebastiano; D′Abbondanza, Marco; Proietti, Marco; Zaccone, Vincenzo; Pes, Chiara; Caradio, Federica; Mattioli, Massimo; Piano, Salvatore; Marra, Alberto Maria; Nobili, Alessandro; Mannucci, Pier Mannuccio; Pietrangelo, Antonello; Sesti, Giorgio; Buzzetti, Elena; Salzano, Andrea; Cimellaro, Antonio
• Other Names: Mannucci Pier Mannuccio investigator.; Nobili Alessandro investigator.; Sesti Giorgio investigator.; Pietrangelo Antonello investigator.; Perticone Francesco investigator.; Violi Francesco investigator.; Corazza Gino Roberto investigator.; Corrao Salvatore investigator.; Marengoni Alessandra investigator.; Salerno Francesco investigator.; Cesari Matteo investigator.; Tettamanti Mauro investigator.; Pasina Luca investigator.; Franchi Carlotta investigator.; Franchi Carlotta investigator.; Novella Alessio investigator.; Tettamanti Mauro investigator.; Miglio Gabriella investigator.; Tettamanti Mauro investigator.; Galbussera Alessia Antonella investigator.; Ardoino Ilaria investigator.; Novella Alessio investigator.; Prisco Domenico investigator.; Silvestri Elena investigator.; Emmi Giacomo investigator.; Bettiol Alessandra investigator.; Mattioli Irene investigator.; Biolo Gianni investigator.; Zanetti Michela investigator.; Bartelloni Giacomo investigator.; Zaccari Michele investigator.; Chiuch Massimiliano investigator.; Vanoli Massimo investigator.; Grignani Giulia investigator.; Pulixi Edoardo Alessandro investigator.; Pirro Matteo investigator.; Lupattelli Graziana investigator.; Bianconi Vanessa investigator.; Alcidi Riccardo investigator.; Giotta Alessia investigator.; Mannarino Massimo R. investigator.; Girelli Domenico investigator.; Busti Fabiana investigator.; Marchi Giacomo investigator.; Barbagallo Mario investigator.; Dominguez Ligia investigator.; Beneduce Vincenza investigator.; Cacioppo Federica investigator.; Corrao Salvatore investigator.; Natoli Giuseppe investigator.; Mularo Salvatore investigator.; Raspanti Massimo investigator.; Argano Christiano investigator.; Cavallaro Federica investigator.; Zoli Marco investigator.; Matacena Maria Laura investigator.; Orio Giuseppe investigator.; Magnolfi Eleonora investigator.; Serafini Giovanni investigator.; Simili Angelo investigator.; Brunori Mattia investigator.; Lazzari Ilaria investigator.; Simili Angelo investigator.; Cappellini Maria Domenica investigator.; Fabio Giovanna investigator.; De Amicis Margherita Migone investigator.; De Luca Giacomo investigator.; Scaramellini Natalia investigator.; Di Stefano Valeria investigator.; Leoni Simona investigator.; Seghezzi Sonia investigator.; Di Mauro Alessandra Danuto investigator.; Maira Diletta investigator.; Mancarella Marta investigator.; Lucchi Tiziano investigator.; Rossi Paolo Dionigi investigator.; Clerici Marta investigator.; Leoni Simona investigator.; Di Mauro Alessandra Danuta investigator.; Bonini Giulia investigator.; Conti Federica investigator.; Prolo Silvia investigator.; Fabrizi Maddalena investigator.; Martelengo Miriana investigator.; Vigani Giulia investigator.; Di Sabatino Antonio investigator.; Miceli Emanuela investigator.; Lenti Marco Vincenzo investigator.; Pisati Martina investigator.; Pitotti Lavinia investigator.; Padula Donatella investigator.; Antoci Valentina investigator.; Cambiè Ginevra investigator.; Pontremoli Roberto investigator.; Beccati Valentina investigator.; Nobili Giulia investigator.; Leoncini Giovanna investigator.; Alberto Jacopo investigator.; Cattaneo Federico investigator.; Anastasio Luigi investigator.; Sofia Lucia investigator.; Carbone Maria investigator.; Cipollone Francesco investigator.; Guagnano Maria Teresa investigator.; Rossi Ilaria investigator.; Valeriani Emanuele investigator.; D'Ardes Damiani investigator.; Esposito Lucia investigator.; Sestili Simona investigator.; Angelucci Ermanno investigator.; Mancuso Gerardo investigator.; Calipari Daniela investigator.; Bartone Mosè investigator.; Delitala Giuseppe investigator.; Berria Maria investigator.; Delitala Alessandro investigator.; Muscaritoli Maurizio investigator.; Molfino Alessio investigator.; Petrillo Enrico investigator.; Giorgi Antonella investigator.; Gracin Christian investigator.; Imbimbo Giovanni investigator.; Zuccalà Giuseppe investigator.; D'Aurizio Gabriella investigator.; Romanelli Giuseppe investigator.; Marengoni Alessandra investigator.; Volpini Andrea investigator.; Lucente Daniela investigator.; Manzoni Francesca investigator.; Pirozzi Annalisa investigator.; Zucchelli Alberto investigator.; Picardi Antonio investigator.; Gentilucci Umberto Vespasiani investigator.; Gallo Paolo investigator.; Dell'Unto Chiara investigator.; Bellelli Giuseppe investigator.; Corsi Maurizio investigator.; Antonucci Cesare investigator.; Sidoli Chiara investigator.; Principato Giulia investigator.; Bonfanti Alessandra investigator.; Szabo Hajnalka investigator.; Mazzola Paolo investigator.; Piazzoli Andrea investigator.; Corsi Maurizio investigator.; Arturi Franco investigator.; Succurro Elena investigator.; Tassone Bruno investigator.; Giofrè Federica investigator.; Serra Maria Grazia investigator.; Bleve Maria Antonietta investigator.; Brucato Antonio investigator.; De Falco Teresa investigator.; Negro Enrica investigator.; Brenna Martino investigator.; Trotta Lucia investigator.; Squintani Giovanni Lorenzo investigator.; Randi Maria Luisa investigator.; Fabris Fabrizio investigator.; Bertozzi Irene investigator.; Bogoni Giulia investigator.; Rabuini Maria Victoria investigator.; Prandini Tancredi investigator.; Ratti Francesco investigator.; Zurlo Chiara investigator.; Cerruti Lorenzo investigator.; Cosi Elisabetta investigator.; Manfredini Roberto investigator.; Fabbian Fabio investigator.; Boari Benedetta investigator.; De Giorgi Alfredo investigator.; Tiseo Ruana investigator.; Paolisso Giuseppe investigator.; Rizzo Maria Rosaria investigator.; Catalano Claudia investigator.; Di Meo Irene investigator.; Borghi Claudio investigator.; Strocchi Enrico investigator.; Ianniello Eugenia investigator.; Soldati Mario investigator.; Schiavone Silvia investigator.; Bragagni Alessio investigator.; Leoni Francesca Giulia investigator.; De Sando Valeria investigator.; Scarduelli Sara investigator.; Cammarosano Michela investigator.; Pareo Ilenia investigator.; Sabbà Carlo investigator.; Vella Francesco Saverio investigator.; Suppressa Patrizia investigator.; De Vincenzo Giovanni Michele investigator.; Comitangelo Alessio investigator.; Amoruso Emanuele investigator.; Custodero Carlo investigator.; Re Giuseppe investigator.; Schilardi Andrea investigator.; Loparco Francesca investigator.; Fenoglio Luigi investigator.; Falcetta Andrea investigator.; Giraudo Alessia Valentina investigator.; D'Aniano Salvatore investigator.; Fracanzani Anna L. investigator.; Tiraboschi Silvia investigator.; Cespiati Annalisa investigator.; Oberti Giovanna investigator.; Sigon Giordano investigator.; Cinque Felice investigator.; Peyvandi Flora investigator.; Rossio Raffaella investigator.; Colombo Giulia investigator.; Agosti Pasquale investigator.; Pagliaro Erica investigator.; Semproni Eleonora investigator.; Ciro Canetta investigator.; Monzani Valter investigator.; Savojardo Valeria investigator.; Ceriani Giuliana investigator.; Folli Christian investigator.; Salerno Francesco investigator.; Pallini Giada investigator.; Montecucco Fabrizio investigator.; Ottonello Luciano investigator.; Caserza Lara investigator.; Vischi Giulia investigator.; Kassem Salam investigator.; Liberale Luca investigator.; Liberato Nicola Lucio investigator.; Tognin Tiziana investigator.; Purrello Francesco investigator.; Di Pino Antonino investigator.; Piro Salvatore investigator.; Rozzini Renzo investigator.; Falanga Lina investigator.; Pisciotta Maria Stella investigator.; Bellucci Francesco Baffa investigator.; Buffelli Stefano investigator.; Ferrandina Camillo investigator.; Mazzeo Francesca investigator.; Spazzini Elena investigator.; Cono Giulia investigator.; Cesaroni Giulia investigator.; Montrucchio Giuseppe investigator.; Peasso Paolo investigator.; Favale Edoardo investigator.; Poletto Cesare investigator.; Margaria Carl investigator.; Sanino Maura investigator.; Violi Francesco investigator.; Perri Ludovica investigator.; Guasti Luigina investigator.; Rotunno Francesca investigator.; Castiglioni Luana investigator.; Maresca Andrea investigator.; Squizzato Alessandro investigator.; Campiotti Leonardo investigator.; Grossi Alessandra investigator.; Diprizio Roberto Davide investigator.; Dentali Francesco investigator.; Bertolotti Marco investigator.; Mussi Chiara investigator.; Lancellotti Giulia investigator.; Libbra Maria Vittoria investigator.; Galassi Matteo investigator.; Grassi Yasmine investigator.; Greco Alessio investigator.; Bigi Elena investigator.; Pellegrini Elisa investigator.; Orlandi Laura investigator.; Dondi Giulia investigator.; Carulli Lucia investigator.; Sciacqua Angela investigator.; Perticone Maria investigator.; Battaglia Rosa investigator.; Maio Raffaele investigator.; Scozzafava Aleandra investigator.; Condoleo Valentino investigator.; Falbo Tania investigator.; Colangelo Lidia investigator.; Filice Marco investigator.; Clausi Elvira investigator.; Stanghellini Vincenzo investigator.; Ruggeri Eugenio investigator.; del Vecchio Sara investigator.; Benzoni Ilaria investigator.; Salvi Andrea investigator.; Leonardi Roberto investigator.; Damiani Giampaolo investigator.; Moroncini Gianluca investigator.; Capeci William investigator.; Mattioli Massimo investigator.; Martino Giuseppe Pio investigator.; Biondi Lorenzo investigator.; Pettinari Pietro investigator.; Ormas Monica investigator.; Filippini Emanuele investigator.; Benfaremo Devis investigator.; Romiti Roberto investigator.; Ghio Riccardo investigator.; Col Anna Dal investigator.; Minisola Salvatore investigator.; Colangelo Luciano investigator.; Cilli Mirella investigator.; Labbadia Giancarlo investigator.; Afeltra Antonella investigator.; Marigliano Benedetta investigator.; Pipita Maria Elena investigator.; Castellino Pietro investigator.; Zanoli Luca investigator.; Gennaro Alfio investigator.; Gaudio Agostino investigator.; Pignataro Samuele investigator.; Mete Francesca investigator.; Gino Miriam investigator.; Moreo Guido investigator.; Prolo Silvia investigator.; Pina Gloria investigator.; Ballestrero Alberto investigator.; Ferrando Fabio investigator.; Gonella Roberta investigator.; Cerminara Domenico investigator.; Setti Paolo investigator.; Traversa Chiara investigator.; Scarsi Camilla investigator.; Graziella Bruno investigator.; Baldassarre Stefano investigator.; Fragapani Salvatore investigator.; Gruden Gabriella investigator.; Berti Franco investigator.; Famularo Giuseppe investigator.; Tarsitani Patrizia investigator.; Castello Roberto investigator.; Pasino Michela investigator.; Ceda Marcello Giuseppe Maggio Gian Paolo investigator.; Morganti Simonetta investigator.; Artoni Andrea investigator.; Grossi Margherita investigator.; Del Giacco Stefano investigator.; Firinu Davide investigator.; Costanzo Giulia investigator.; Argiolas Giacomo investigator.; Paoletti Giovanni investigator.; Losa Francesca investigator.; Montalto Giuseppe investigator.; Licata Anna investigator.; Montalto Filippo Alessandro investigator.; Corica Francesco investigator.; Basile Giorgio investigator.; Catalano Antonino investigator.; Bellone Federica investigator.; Principato Concetto investigator.; Malatino Lorenzo investigator.; Stancanelli Benedetta investigator.; Terranova Valentina investigator.; Di Marca Salvatore investigator.; Di Quattro Rosario investigator.; La Malfa Lara investigator.; Caruso Rossella investigator.; Mecocci Patrizia investigator.; Ruggiero Carmelinda investigator.; Boccardi Virginia investigator.; Meschi Tiziana investigator.; Ticinesi Andrea investigator.; Nouvenne Antonio investigator.; Minuz Pietro investigator.; Fondrieschi Luigi investigator.; Imperiale Giandomenico Nigro investigator.; Morellini Sarah investigator.; Pirisi Mario investigator.; Fra Gian Paolo investigator.; Sola Daniele investigator.; Bellan Mattia investigator.; Quadri Roberto investigator.; Larovere Erica investigator.; Novelli Marco investigator.; Simeone Emilio investigator.; Scurti Rosa investigator.; Tolloso Fabio investigator.; Tarquini Roberto investigator.; Valoriani Alice investigator.; Dolenti Silvia investigator.; Vannini Giulia investigator.; Volpi Riccardo investigator.; Bocchi Pietro investigator.; Vignali Alessandro investigator.; Harari Sergio investigator.; Lonati Chiara investigator.; Napoli Federico investigator.; Aiello Italia investigator.; Purrello Francesco investigator.; Di Pino Antonino investigator.; Salvatore Teresa investigator.; Monaco Lucio investigator.; Ricozzi Carmen investigator.; Pilotto Alberto investigator.; Indiano Ilaria investigator.; Gandolfo Federica investigator.; Pasini Franco Laghi investigator.; Capecchi Pier Leopoldo investigator.; Nuti Ranuccio investigator.; Valenti Roberto investigator.; Ruvio Martina investigator.; Cappelli Silvia investigator.; Palazzuoli Alberto investigator.; Bernardi Mauro investigator.; Bassi Silvia Li investigator.; Santi Luca investigator.; Zaccherini Giacomo investigator.; Durante Vittorio investigator.; Tirotta Daniela investigator.; Eusebi Giovanna investigator.; Cattaneo Marco investigator.; Amoruso Maria Valentina investigator.; Fracasso Paola investigator.; Fasolino Cristina investigator.; Tresoldi Moreno investigator.; Bozzolo Enrica investigator.; Damanti Sarah investigator.; Porta Massimo investigator.; Gino Miriam investigator.; Armentaro Giuseppe investigator.; Arnone Maria Immacolata investigator.; Barone Milena investigator.; Bertolino Lorenzo investigator.; Bianco Sara investigator.; Binello Nicolò investigator.; Brancati Simona investigator.; Buonauro Agostino investigator.; Buzzetti Elena investigator.; Capeci William investigator.; Caradio Federica investigator.; Cicco Sebastiano investigator.; Cimellaro Antonio investigator.; Cordeddu William investigator.; Curcio Rosa investigator.; Dalbeni Andrea investigator.; D'Abbondanza Marco investigator.; D'Agnano Salvatore investigator.; D'Ardes Damiano investigator.; De Feo Martina investigator.; Di Marca Salvatore investigator.; Donnarumma Emilia investigator.; Fei Marco investigator.; Filippini Emanuele investigator.; Gambino Carmine Gabriele investigator.; Giorgini Paolo investigator.; Lombardi Rosa investigator.; Marra Alberto Maria investigator.; Mattioli Massimo investigator.; Miceli Giuseppe investigator.; Naccarato Paola investigator.; Noviello Silvia investigator.; Olivieri Gaia investigator.; Padula Donatella investigator.; Parente Roberta investigator.; Pes Chiara investigator.; Piano Salvatore investigator.; Pignataro Francesca Serena investigator.; Poma Sonia investigator.; Porceddu Enrica investigator.; Pucci Giacomo investigator.; Ricchio Marco investigator.; Sabena Anna investigator.; Salice Marco investigator.; Salzano Andrea investigator.; Santarossa Claudia investigator.; Savona Ambra investigator.; Savrié Caterina investigator.; Scicali Roberto investigator.; Stabile Mario investigator.; Talerico Giovanni investigator.; Talia Michela investigator.; Tassone Eliezer Joseph investigator.; Teatini Thomas investigator.; Tombolini Elisabetta investigator.; Traversa Matteo investigator.; Vettore Elia investigator.; Vignal Alessandro investigator.; Vilardi Luca investigator.; Villani Rosanna investigator.; Vitale Francesco investigator.; Mannucci Pier Mannuccio investigator.; Nobili Alessandro investigator.; Sesti Giorgio investigator.; Pietrangelo Antonello investigator.; Perticone Francesco investigator.; Violi Francesco investigator.; Corazza Gino Roberto investigator.; Corrao Salvatore investigator.; Marengoni Alessandra investigator.; Salerno Francesco investigator.; Cesari Matteo investigator.; Tettamanti Mauro investigator.; Pasina Luca investigator.; Franchi Carlotta investigator.; Franchi Carlotta investigator.; Novella Alessio investigator.; Tettamanti Mauro investigator.; Miglio Gabriella investigator.; Tettamanti Mauro investigator.; Galbussera Alessia Antonella investigator.; Ardoino Ilaria investigator.; Novella Alessio investigator.; Prisco Domenico investigator.; Silvestri Elena investigator.; Emmi Giacomo investigator.; Bettiol Alessandra investigator.; Mattioli Irene investigator.; Biolo Gianni investigator.; Zanetti Michela investigator.; Bartelloni Giacomo investigator.; Zaccari Michele investigator.; Chiuch Massimiliano investigator.; Vanoli Massimo investigator.; Grignani Giulia investigator.; Pulixi Edoardo Alessandro investigator.; Pirro Matteo investigator.; Lupattelli Graziana investigator.; Bianconi Vanessa investigator.; Alcidi Riccardo investigator.; Giotta Alessia investigator.; Mannarino Massimo R. investigator.; Girelli Domenico investigator.; Busti Fabiana investigator.; Marchi Giacomo investigator.; Barbagallo Mario investigator.; Dominguez Ligia investigator.; Beneduce Vincenza investigator.; Cacioppo Federica investigator.; Corrao Salvatore investigator.; Natoli Giuseppe investigator.; Mularo Salvatore investigator.; Raspanti Massimo investigator.; Argano Christiano investigator.; Cavallaro Federica investigator.; Zoli Marco investigator.; Matacena Maria Laura investigator.; Orio Giuseppe investigator.; Magnolfi Eleonora investigator.; Serafini Giovanni investigator.; Simili Angelo investigator.; Brunori Mattia investigator.; Lazzari Ilaria investigator.; Simili Angelo investigator.; Cappellini Maria Domenica investigator.; Fabio Giovanna investigator.; De Amicis Margherita Migone investigator.; De Luca Giacomo investigator.; Scaramellini Natalia investigator.; Di Stefano Valeria investigator.; Leoni Simona investigator.; Seghezzi Sonia investigator.; Di Mauro Alessandra Danuto investigator.; Maira Diletta investigator.; Mancarella Marta investigator.; Lucchi Tiziano investigator.; Rossi Paolo Dionigi investigator.; Clerici Marta investigator.; Leoni Simona investigator.; Di Mauro Alessandra Danuta investigator.; Bonini Giulia investigator.; Conti Federica investigator.; Prolo Silvia investigator.; Fabrizi Maddalena investigator.; Martelengo Miriana investigator.; Vigani Giulia investigator.; Di Sabatino Antonio investigator.; Miceli Emanuela investigator.; Lenti Marco Vincenzo investigator.; Pisati Martina investigator.; Pitotti Lavinia investigator.; Padula Donatella investigator.; Antoci Valentina investigator.; Cambiè Ginevra investigator.; Pontremoli Roberto investigator.; Beccati Valentina investigator.; Nobili Giulia investigator.; Leoncini Giovanna investigator.; Alberto Jacopo investigator.; Cattaneo Federico investigator.; Anastasio Luigi investigator.; Sofia Lucia investigator.; Carbone Maria investigator.; Cipollone Francesco investigator.; Guagnano Maria Teresa investigator.; Rossi Ilaria investigator.; Valeriani Emanuele investigator.; D'Ardes Damiani investigator.; Esposito Lucia investigator.; Sestili Simona investigator.; Angelucci Ermanno investigator.; Mancuso Gerardo investigator.; Calipari Daniela investigator.; Bartone Mosè investigator.; Delitala Giuseppe investigator.; Berria Maria investigator.; Delitala Alessandro investigator.; Muscaritoli Maurizio investigator.; Molfino Alessio investigator.; Petrillo Enrico investigator.; Giorgi Antonella investigator.; Gracin Christian investigator.; Imbimbo Giovanni investigator.; Zuccalà Giuseppe investigator.; D'Aurizio Gabriella investigator.; Romanelli Giuseppe investigator.; Marengoni Alessandra investigator.; Volpini Andrea investigator.; Lucente Daniela investigator.; Manzoni Francesca investigator.; Pirozzi Annalisa investigator.; Zucchelli Alberto investigator.; Picardi Antonio investigator.; Gentilucci Umberto Vespasiani investigator.; Gallo Paolo investigator.; Dell'Unto Chiara investigator.; Bellelli Giuseppe investigator.; Corsi Maurizio investigator.; Antonucci Cesare investigator.; Sidoli Chiara investigator.; Principato Giulia investigator.; Bonfanti Alessandra investigator.; Szabo Hajnalka investigator.; Mazzola Paolo investigator.; Piazzoli Andrea investigator.; Corsi Maurizio investigator.; Arturi Franco investigator.; Succurro Elena investigator.; Tassone Bruno investigator.; Giofrè Federica investigator.; Serra Maria Grazia investigator.; Bleve Maria Antonietta investigator.; Brucato Antonio investigator.; De Falco Teresa investigator.; Negro Enrica investigator.; Brenna Martino investigator.; Trotta Lucia investigator.; Squintani Giovanni Lorenzo investigator.; Randi Maria Luisa investigator.; Fabris Fabrizio investigator.; Bertozzi Irene investigator.; Bogoni Giulia investigator.; Rabuini Maria Victoria investigator.; Prandini Tancredi investigator.; Ratti Francesco investigator.; Zurlo Chiara investigator.; Cerruti Lorenzo investigator.; Cosi Elisabetta investigator.; Manfredini Roberto investigator.; Fabbian Fabio investigator.; Boari Benedetta investigator.; De Giorgi Alfredo investigator.; Tiseo Ruana investigator.; Paolisso Giuseppe investigator.; Rizzo Maria Rosaria investigator.; Catalano Claudia investigator.; Di Meo Irene investigator.; Borghi Claudio investigator.; Strocchi Enrico investigator.; Ianniello Eugenia investigator.; Soldati Mario investigator.; Schiavone Silvia investigator.; Bragagni Alessio investigator.; Leoni Francesca Giulia investigator.; De Sando Valeria investigator.; Scarduelli Sara investigator.; Cammarosano Michela investigator.; Pareo Ilenia investigator.; Sabbà Carlo investigator.; Vella Francesco Saverio investigator.; Suppressa Patrizia investigator.; De Vincenzo Giovanni Michele investigator.; Comitangelo Alessio investigator.; Amoruso Emanuele investigator.; Custodero Carlo investigator.; Re Giuseppe investigator.; Schilardi Andrea investigator.; Loparco Francesca investigator.; Fenoglio Luigi investigator.; Falcetta Andrea investigator.; Giraudo Alessia Valentina investigator.; D'Aniano Salvatore investigator.; Fracanzani Anna L. investigator.; Tiraboschi Silvia investigator.; Cespiati Annalisa investigator.; Oberti Giovanna investigator.; Sigon Giordano investigator.; Cinque Felice investigator.; Peyvandi Flora investigator.; Rossio Raffaella investigator.; Colombo Giulia investigator.; Agosti Pasquale investigator.; Pagliaro Erica investigator.; Semproni Eleonora investigator.; Ciro Canetta investigator.; Monzani Valter investigator.; Savojardo Valeria investigator.; Ceriani Giuliana investigator.; Folli Christian investigator.; Salerno Francesco investigator.; Pallini Giada investigator.; Montecucco Fabrizio investigator.; Ottonello Luciano investigator.; Caserza Lara investigator.; Vischi Giulia investigator.; Kassem Salam investigator.; Liberale Luca investigator.; Liberato Nicola Lucio investigator.; Tognin Tiziana investigator.; Purrello Francesco investigator.; Di Pino Antonino investigator.; Piro Salvatore investigator.; Rozzini Renzo investigator.; Falanga Lina investigator.; Pisciotta Maria Stella investigator.; Bellucci Francesco Baffa investigator.; Buffelli Stefano investigator.; Ferrandina Camillo investigator.; Mazzeo Francesca investigator.; Spazzini Elena investigator.; Cono Giulia investigator.; Cesaroni Giulia investigator.; Montrucchio Giuseppe investigator.; Peasso Paolo investigator.; Favale Edoardo investigator.; Poletto Cesare investigator.; Margaria Carl investigator.; Sanino Maura investigator.; Violi Francesco investigator.; Perri Ludovica investigator.; Guasti Luigina investigator.; Rotunno Francesca investigator.; Castiglioni Luana investigator.; Maresca Andrea investigator.; Squizzato Alessandro investigator.; Campiotti Leonardo investigator.; Grossi Alessandra investigator.; Diprizio Roberto Davide investigator.; Dentali Francesco investigator.; Bertolotti Marco investigator.; Mussi Chiara investigator.; Lancellotti Giulia investigator.; Libbra Maria Vittoria investigator.; Galassi Matteo investigator.; Grassi Yasmine investigator.; Greco Alessio investigator.; Bigi Elena investigator.; Pellegrini Elisa investigator.; Orlandi Laura investigator.; Dondi Giulia investigator.; Carulli Lucia investigator.; Sciacqua Angela investigator.; Perticone Maria investigator.; Battaglia Rosa investigator.; Maio Raffaele investigator.; Scozzafava Aleandra investigator.; Condoleo Valentino investigator.; Falbo Tania investigator.; Colangelo Lidia investigator.; Filice Marco investigator.; Clausi Elvira investigator.; Stanghellini Vincenzo investigator.; Ruggeri Eugenio investigator.; del Vecchio Sara investigator.; Benzoni Ilaria investigator.; Salvi Andrea investigator.; Leonardi Roberto investigator.; Damiani Giampaolo investigator.; Moroncini Gianluca investigator.; Capeci William investigator.; Mattioli Massimo investigator.; Martino Giuseppe Pio investigator.; Biondi Lorenzo investigator.; Pettinari Pietro investigator.; Ormas Monica investigator.; Filippini Emanuele investigator.; Benfaremo Devis investigator.; Romiti Roberto investigator.; Ghio Riccardo investigator.; Col Anna Dal investigator.; Minisola Salvatore investigator.; Colangelo Luciano investigator.; Cilli Mirella investigator.; Labbadia Giancarlo investigator.; Afeltra Antonella investigator.; Marigliano Benedetta investigator.; Pipita Maria Elena investigator.; Castellino Pietro investigator.; Zanoli Luca investigator.; Gennaro Alfio investigator.; Gaudio Agostino investigator.; Pignataro Samuele investigator.; Mete Francesca investigator.; Gino Miriam investigator.; Moreo Guido investigator.; Prolo Silvia investigator.; Pina Gloria investigator.; Ballestrero Alberto investigator.; Ferrando Fabio investigator.; Gonella Roberta investigator.; Cerminara Domenico investigator.; Setti Paolo investigator.; Traversa Chiara investigator.; Scarsi Camilla investigator.; Graziella Bruno investigator.; Baldassarre Stefano investigator.; Fragapani Salvatore investigator.; Gruden Gabriella investigator.; Berti Franco investigator.; Famularo Giuseppe investigator.; Tarsitani Patrizia investigator.; Castello Roberto investigator.; Pasino Michela investigator.; Ceda Marcello Giuseppe Maggio Gian Paolo investigator.; Morganti Simonetta investigator.; Artoni Andrea investigator.; Grossi Margherita investigator.; Del Giacco Stefano investigator.; Firinu Davide investigator.; Costanzo Giulia investigator.; Argiolas Giacomo investigator.; Paoletti Giovanni investigator.; Losa Francesca investigator.; Montalto Giuseppe investigator.; Licata Anna investigator.; Montalto Filippo Alessandro investigator.; Corica Francesco investigator.; Basile Giorgio investigator.; Catalano Antonino investigator.; Bellone Federica investigator.; Principato Concetto investigator.; Malatino Lorenzo investigator.; Stancanelli Benedetta investigator.; Terranova Valentina investigator.; Di Marca Salvatore investigator.; Di Quattro Rosario investigator.; La Malfa Lara investigator.; Caruso Rossella investigator.; Mecocci Patrizia investigator.; Ruggiero Carmelinda investigator.; Boccardi Virginia investigator.; Meschi Tiziana investigator.; Ticinesi Andrea investigator.; Nouvenne Antonio investigator.; Minuz Pietro investigator.; Fondrieschi Luigi investigator.; Imperiale Giandomenico Nigro investigator.; Morellini Sarah investigator.; Pirisi Mario investigator.; Fra Gian Paolo investigator.; Sola Daniele investigator.; Bellan Mattia investigator.; Quadri Roberto investigator.; Larovere Erica investigator.; Novelli Marco investigator.; Simeone Emilio investigator.; Scurti Rosa investigator.; Tolloso Fabio investigator.; Tarquini Roberto investigator.; Valoriani Alice investigator.; Dolenti Silvia investigator.; Vannini Giulia investigator.; Volpi Riccardo investigator.; Bocchi Pietro investigator.; Vignali Alessandro investigator.; Harari Sergio investigator.; Lonati Chiara investigator.; Napoli Federico investigator.; Aiello Italia investigator.; Purrello Francesco investigator.; Di Pino Antonino investigator.; Salvatore Teresa investigator.; Monaco Lucio investigator.; Ricozzi Carmen investigator.; Pilotto Alberto investigator.; Indiano Ilaria investigator.; Gandolfo Federica investigator.; Pasini Franco Laghi investigator.; Capecchi Pier Leopoldo investigator.; Nuti Ranuccio investigator.; Valenti Roberto investigator.; Ruvio Martina investigator.; Cappelli Silvia investigator.; Palazzuoli Alberto investigator.; Bernardi Mauro investigator.; Bassi Silvia Li investigator.; Santi Luca investigator.; Zaccherini Giacomo investigator.; Durante Vittorio investigator.; Tirotta Daniela investigator.; Eusebi Giovanna investigator.; Cattaneo Marco investigator.; Amoruso Maria Valentina investigator.; Fracasso Paola investigator.; Fasolino Cristina investigator.; Tresoldi Moreno investigator.; Bozzolo Enrica investigator.; Damanti Sarah investigator.; Porta Massimo investigator.; Gino Miriam investigator.; Armentaro Giuseppe investigator.; Arnone Maria Immacolata investigator.; Barone Milena investigator.; Bertolino Lorenzo investigator.; Bianco Sara investigator.; Binello Nicolò investigator.; Brancati Simona investigator.; Buonauro Agostino investigator.; Buzzetti Elena investigator.; Capeci William investigator.; Caradio Federica investigator.; Cicco Sebastiano investigator.; Cimellaro Antonio investigator.; Cordeddu William investigator.; Curcio Rosa investigator.; Dalbeni Andrea investigator.; D'Abbondanza Marco investigator.; D'Agnano Salvatore investigator.; D'Ardes Damiano investigator.; De Feo Martina investigator.; Di Marca Salvatore investigator.; Donnarumma Emilia investigator.; Fei Marco investigator.; Filippini Emanuele investigator.; Gambino Carmine Gabriele investigator.; Giorgini Paolo investigator.; Lombardi Rosa investigator.; Marra Alberto Maria investigator.; Mattioli Massimo investigator.; Miceli Giuseppe investigator.; Naccarato Paola investigator.; Noviello Silvia investigator.; Olivieri Gaia investigator.; Padula Donatella investigator.; Parente Roberta investigator.; Pes Chiara investigator.; Piano Salvatore investigator.; Pignataro Francesca Serena investigator.; Poma Sonia investigator.; Porceddu Enrica investigator.; Pucci Giacomo investigator.; Ricchio Marco investigator.; Sabena Anna investigator.; Salice Marco investigator.; Salzano Andrea investigator.; Santarossa Claudia investigator.; Savona Ambra investigator.; Savrié Caterina investigator.; Scicali Roberto investigator.; Stabile Mario investigator.; Talerico Giovanni investigator.; Talia Michela investigator.; Tassone Eliezer Joseph investigator.; Teatini Thomas investigator.; Tombolini Elisabetta investigator.; Traversa Matteo investigator.; Vettore Elia investigator.; Vignali Alessandro investigator.; Vilardi Luca investigator.; Villani Rosanna investigator.; Vitale Francesco investigator.;
• Is Part Of: European journal of clinical investigation. Volume 53:Number 4(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-12-21
• Subjects: antihypertensive drugs -- cardiovascular events -- hypertension -- older patients -- survival; Pathology -- Periodicals; Medical research -- Periodicals; 616.075
• DOI: 10.1111/eci.13931
• Languages: English
• ISSNs: 0014-2972

Abstract

Abstract: Background: Hypertension management in older patients represents a challenge, particularly when hospitalized. Objective: The objective of this study is to investigate the determinants and related outcomes of antihypertensive drug prescription in a cohort of older hospitalized patients. Methods: A total of 5671 patients from REPOSI (a prospective multicentre observational register of older Italian in‐patients from internal medicine or geriatric wards) were considered; 4377 (77.2%) were hypertensive. Minimum treatment (MT) for hypertension was defined according to the 2018 ESC guidelines [an angiotensin‐converting‐enzyme‐inhibitor (ACE‐I) or an angiotensin‐receptor‐blocker (ARB) with a calcium‐channel‐blocker (CCB) and/or a thiazide diuretic; if >80 years old, an ACE‐I or ARB or CCB or thiazide diuretic]. Determinants of MT discontinuation at discharge were assessed. Study outcomes were any cause rehospitalization/all cause death, all‐cause death, cardiovascular (CV) hospitalization/death, CV death, non‐CV death, evaluated according to the presence of MT at discharge. Results: Hypertensive patients were older than normotensives, with a more impaired functional status, higher burden of comorbidity and polypharmacy. A total of 2233 patients were on MT at admission, 1766 were on MT at discharge. Discontinuation of MT was associated with the presence of comorbidities (lower odds for diabetes, higher odds for chronic kidney disease and dementia). An adjusted multivariable logistic regression analysis showed that MT for hypertension at discharge was associated with lower risk of all‐cause death, all‐cause death/hospitalization, CV death, CV death/hospitalization and non‐CV death. Conclusions: Guidelines‐suggested MT for hypertension at discharge is associated with a lower risk of adverse clinical outcomes. Nevertheless, changes in antihypertensive treatment still occur in a significant proportion of older hospitalized patients. Abstract : In this observational cohort study, we investigated the impact of hospitalization on changes in antihypertensive therapy in 5671 hypertensive older inpatients from the REPOSI register. Fifty‐one percent of patients were on minimum treatment (MT, defined according to the 2018 ESC guidelines) at admission. This percentage reduced to 40% at discharge, mostly due to specific clinical impairment and comorbidities such as chronic kidney disease and dementia. Maintaining a MT at discharge was associated with a lower risk of major clinical outcomes.