TDM is dead. Long live TCI!. Issue 4 (1st July 2020)
- Record Type:
- Journal Article
- Title:
- TDM is dead. Long live TCI!. Issue 4 (1st July 2020)
- Main Title:
- TDM is dead. Long live TCI!
- Authors:
- Holford, Nick
Ma, Guangda
Metz, David - Other Names:
- Bies Rob guestEditor.
Wright Dan guestEditor. - Abstract:
- Abstract : Twenty years ago, target concentration intervention (TCI) was distinguished from therapeutic drug monitoring (TDM). It was proposed that TCI would bring more clinical benefit because of the precision of the approach and the ability to link TCI to principles of pharmacokinetics and pharmacodynamics to predict the dose required by an individual (1). We examine the theory and clinical trial evidence supporting the benefits of TCI over TDM and conclude that in the digital age TDM should be abandoned and replaced by TCI.
- Is Part Of:
- British journal of clinical pharmacology. Volume 88:Issue 4(2022)
- Journal:
- British journal of clinical pharmacology
- Issue:
- Volume 88:Issue 4(2022)
- Issue Display:
- Volume 88, Issue 4 (2022)
- Year:
- 2022
- Volume:
- 88
- Issue:
- 4
- Issue Sort Value:
- 2022-0088-0004-0000
- Page Start:
- 1406
- Page End:
- 1413
- Publication Date:
- 2020-07-01
- Subjects:
- Pharmacology -- Periodicals
Drugs -- Periodicals
615.1 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2125 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1111/bcp.14434 ↗
- Languages:
- English
- ISSNs:
- 0306-5251
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 2307.180000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 26308.xml