123I Scintigraphy Mirror Image of Graves Disease Induced by Radioiodine Treatment for Toxic Adenoma. (February 2022)

• Record Type: Journal Article
• Authors: Lugat, Alexandre; Drui, Delphine; Bach-Ngohou, Kalyane; Guillot, Pascale; Mourrain-Langlois, Emmanuelle; Kraeber-Bodéré, Françoise; Ansquer, Catherine
• Is Part Of: Clinical nuclear medicine. Volume 47:Number 2(2022)
• Publication Date: 2022-02
• Subjects: 123I scintigraphy -- toxic adenoma -- Graves disease -- radioiodine therapy; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003884
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 61-year-old woman presenting with hyperthyroidism received 131 I therapy for a toxic adenoma diagnosed by 123 I scintigraphy. Six months later, the patient had a relapse of hyperthyroidism, and 123 I scintigraphy showed a mirror image of the first scintigraphy: a high and diffuse uptake in the thyroid gland except for the previously treated nodule. Graves disease was confirmed by elevated thyrotropin receptor antibodies. The patient was cured by a second radioiodine therapy. Radioiodine-induced Graves disease may occur within 6 months of 131 I treatment of toxic adenoma and can be treated with a second line of 131 I.