Time to peak enhancement of malignant hypervascular hepatic tumors versus that of the aorta evaluating by test bolus sequence of magnetic resonance imaging. Issue 131 (October 2020)

• Record Type: Journal Article
• Authors: Chiu, Sung-Hua; Shih, Yu-Lueng; Huang, Guo-Shu; Chang, Ping-Ying; Lin, Hsuan-Hwai; Chang, Wei-Chou; Hsu, Hsian-He; Kao, Hung-Wen
• Is Part Of: European journal of radiology. Issue 131(2020)
• Publication Date: 2020-10
• Subjects: Magnetic resonance imaging -- Time factors -- Contrast media -- Liver neoplasms -- Carcinoma -- Hepatocellular -- Neuroendocrine tumors; Medical radiology -- Periodicals; Radiology -- Periodicals; Radiologie médicale -- Périodiques; Medical radiology; Periodicals; 616.075705
• DOI: 10.1016/j.ejrad.2020.109211
• Languages: English
• ISSNs: 0720-048X

Abstract

Highlights: The time to peak enhancement of malignant hypervascular hepatic tumors shows linear correlation with that of the aorta. The time to peak enhancement of liver and pancreas also have linear correlation with that of the aorta. This liner correlation can improve the optimization of scan delay in patient-specific dynamic MR imaging. Abstract: Purpose: To determine the relationship between time to peak enhancement (TPE) of malignant hypervascular hepatic tumors and that of the aorta. Method: Sixty patients with malignant hypervascular hepatic tumors (48 with hepatocellular carcinoma and 12 with metastatic neuroendocrine tumor) who received abdominal MRI with test bolus sequence between January 2015 and May 2019 were enrolled. The test bolus images were monitored every 3 s after the injection of 2 mL gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) and 10 mL saline flush, to evaluate the TPE of the tumors and aorta. We used linear regression with a least squares approach to show the relationship between TPE of the malignant hypervascular hepatic tumors and that of the aorta. Results: TPE of malignant hypervascular hepatic tumors and abdominal aorta were 43.4 ± 12.9 and 23.3 ± 7.4 s, respectively (mean ± standard deviation). In univariate regression analysis, the TPE of malignant hypervascular hepatic tumors have a positively linear correlation with that of the aorta by the following equation: (TPE of malignant hypervascular hepatic tumor) = 1.4 X (TPE of the aorta) + 10.6 s (r = 0.65, p < 0.005). Conclusions: TPE of malignant hypervascular hepatic tumors can be predicted by a simple linear transformation from that of the aorta.