Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field. Issue 5 (27th August 2021)

• Record Type: Journal Article
• Authors: Verger, Antoine; Grimaldi, Stephan; Ribeiro, Maria‐Joao; Frismand, Solène; Guedj, Eric
• Is Part Of: Annals of neurology. Volume 90:Issue 5(2021)
• Page Start: 711
• Page End: 719
• Publication Date: 2021-08-27
• Subjects: Neurology -- Periodicals; Pediatric neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; 616.8
• DOI: 10.1002/ana.26187
• Languages: English
• ISSNs: 0364-5134

Abstract

Abstract : The early differential diagnosis of Parkinson disease and atypical parkinsonism is a major challenge. The use of single photon emission computed tomography (SPECT)/positron emission tomography (PET) molecular imaging to investigate parkinsonism is a fast‐developing field. Imaging biomarker research may potentially lead to more accurate disease detection, enabling earlier diagnosis and treatment. This review summarizes recent SPECT/PET advances in radiopharmaceuticals and imaging technologies/analyses that improve the diagnosis of neurodegenerative parkinsonism. We are currently witnessing a turning point in the field. Integrating molecular imaging as a diagnostic technique represents an opportunity to reassess the strategies for diagnosing neurodegenerative parkinsonism. ANN NEUROL 2021;90:711–719