Oral Contraceptives and Increased Formation of Soluble Fibrin. Issue 5930 (31st August 1974)

• Record Type: Journal Article
• Authors: Pilgeram, L. O.; Ellison, J.; Bussche, G. Von Dem
• Is Part Of: BMJ. Volume 3:Issue 5930(1974)
• Page Start: 556
• Page End: 558
• Publication Date: 1974-08-31
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.3.5930.556
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : Soluble fibrin was measured weekly for two months in 12 normal women and in 12 women on combined oestrogen-progestogen therapy (Ortho-Novin, Norinyl, Enavid, Ovral, Ovulen, Demulen). Plasma soluble fibrin concentration in women on oral contraceptives showed an increase of 97·2% (P <0·001) above that of normal women. In three cases, where each woman on the oral contraceptive served as her own control, stopping medication led to a return to normal of the plasma content of soluble fibrin.