Alkyl Phosphine Free, Metal‐Ligand Cooperative Complex Catalyzed Alcohol Dehydrogenative Coupling Reactions. Issue 6 (22nd April 2021)

• Record Type: Journal Article
• Authors: Roy, Bivas Chandra; Ganguli, Kasturi; Samim, Sk. Abdus; Kundu, Sabuj
• Is Part Of: Asian journal of organic chemistry. Volume 10:Issue 6(2021)
• Page Start: 1218
• Page End: 1232
• Publication Date: 2021-04-22
• Subjects: metal-ligand cooperation -- bifunctional -- acceptorless dehydrogenative coupling -- borrowing hydrogen -- alcohol; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202100034
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: In last two decades alcohol has drawn a special attention as a building blocks due to its abundance, low cost and less toxic nature which can be derived from various sustainable resources. By dehydrogenation of alcohol, aldehyde/ketone can be easily accessed which can be further coupled with several nucleophiles for the construction of complex molecules. Among the various strategies, metal‐ligand cooperation is a powerful and efficient tool for the utilization of alcohol to synthesize variety of value‐added products. Numerous alkyl phosphine based bifunctional complexes are well‐known in the literature for the alcohol dehydrogenative coupling reactions. However, the presence of alkyl phosphine moiety and air and moisture sensitive nature of the metal complexes hinder their broad application in catalysis. In this minireview, we highlighted air and moisture stable, metal‐ligand cooperative 5d, 4d and 3d metal‐based complexes which were effectively utilized to fabricate different value‐added compounds by alcohol dehydrogenative coupling reactions. Abstract : Biomass derived alcohols have served as a cheap, non toxic and renewable altenative for the large scale synthesis of value‐added chemicals. This minireview summarizes the role of different alkyl phosphine free, air and moisture stable, metal‐ligand cooperative 5d, 4d and 3d metal‐based complexes towards the synthesis of different value‐added products following the alcohol dehydrogenative coupling strategy.