Radiation unlocks the therapeutic potential of immune checkpoint blockers in lung cancer patients. (3rd August 2019)
- Record Type:
- Journal Article
- Title:
- Radiation unlocks the therapeutic potential of immune checkpoint blockers in lung cancer patients. (3rd August 2019)
- Main Title:
- Radiation unlocks the therapeutic potential of immune checkpoint blockers in lung cancer patients
- Authors:
- Ko, Eric C.
Galluzzi, Lorenzo - Abstract:
- ABSTRACT: CTLA4 blockers have limited activity in patients with chemorefractory lung cancer. Recent clinical data demonstrate that radiation therapy combined with CTLA4 blockers enables disease control in a sizeable fraction of these patients, correlating with increased circulating levels of type I interferon and dynamic changes in the peripheral T cell repertoire.
- Is Part Of:
- Oncoimmunology. Volume 8:Number 8(2019)
- Journal:
- Oncoimmunology
- Issue:
- Volume 8:Number 8(2019)
- Issue Display:
- Volume 8, Issue 8 (2019)
- Year:
- 2019
- Volume:
- 8
- Issue:
- 8
- Issue Sort Value:
- 2019-0008-0008-0000
- Page Start:
- Page End:
- Publication Date:
- 2019-08-03
- Subjects:
- CGAS -- ipilimumab -- non-small cell lung carcinoma -- STING -- TREX1 -- type I interferon
Tumors -- Immunological aspects -- Periodicals
Neoplasms -- therapy -- Periodicals
Immunotherapy -- Periodicals
616.994 - Journal URLs:
- http://www.landesbioscience.com/journals/oncoimmunology/ ↗
http://www.tandfonline.com/toc/koni20/current ↗
http://www.tandf.co.uk/journals/ ↗ - DOI:
- 10.1080/2162402X.2019.1606624 ↗
- Languages:
- English
- ISSNs:
- 2162-402X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 26182.xml