Lactobacillus bloodstream infections genetically related to probiotic use in pediatric hematopoietic cell transplant patients. (28th March 2023)

• Record Type: Journal Article
• Authors: Gilliam, Craig H.; Brazelton de Cardenas, Jessica; Carias, Delia; Maron Alfaro, Gaby; Hayden, Randall T.; Hakim, Hana
• Is Part Of: Infection control and hospital epidemiology. Volume 44:Number 3(2023)
• Page Start: 484
• Page End: 487
• Publication Date: 2023-03-28
• Subjects: Nosocomial infections -- Epidemiology -- Periodicals; Health facilities -- Sanitation -- Periodicals; Hospital buildings -- Sanitation -- Periodicals; Cross Infection -- Periodicals; Epidemiology -- Periodicals; Hospitals -- Periodicals; Infection Control -- Periodicals; 614.44
• DOI: 10.1017/ice.2021.515
• Languages: English
• ISSNs: 0899-823X

Abstract

Abstract: We describe a cluster of 6 pediatric hematopoietic cell transplant recipients with Lactobacillus bacteremia attributed to probiotic use. Lactobacillus isolates cultured from probiotics and patients' blood were proven to be related using whole-genome sequencing. Clinical studies are needed to evaluate the safety of probiotic use in immunocompromised patients.