Adult T-cell leukemia/lymphoma complicated by Pneumocystis pneumonia in a non-endemic area. (2023)

• Record Type: Journal Article
• Authors: Kunimoto, Mayu; Inomata, Minoru; Chin, Haruka; Ito, Yu; Fujimoto, Kazushi; Muto, Yutaka; Nomura, Moe; Sato, Kota; Sakamoto, Keita; Awano, Nobuyasu; Kuse, Naoyuki; Kumasaka, Toshio; Takemura, Tamiko; Izumo, Takehiro
• Is Part Of: Respiratory medicine case reports. Volume 42(2023)
• Publication Date: 2023
• Subjects: Adult T-cell leukemia/lymphoma (ATLL) -- Human T-cell leukemia virus type 1 (HTLV-1) -- Pneumocystis pneumonia (PCP); ATLL adult T-cell leukemia/lymphoma -- HTLV-1 human T-cell leukemia virus type 1 -- PCP Pneumocystis pneumonia -- CT computed tomography -- LD lactate dehydrogenase -- sIL-2R soluble interleukin-2 receptor -- HRCT high-resolution CT -- GGO ground glass opacity; Respiratory organs -- Diseases -- Periodicals; Chest -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Respiratory System -- Periodicals; Chest -- Diseases; Respiratory organs -- Diseases; Electronic journals; Periodicals; 616.2
• DOI: 10.1016/j.rmcr.2023.101807
• Languages: English
• ISSNs: 2213-0071

Abstract

Abstract: Adult T-cell leukemia/lymphoma (ATLL) is a human T-cell leukemia virus type 1-inducing unevenly-distributed T-cell malignancy, which is often complicated by opportunistic infections. Here, we discuss the case of a 75-year-old woman presenting with Pneumocystis pneumonia (PCP) who was subsequently diagnosed with ATLL in Tokyo, a non-endemic area of ATLL. In addition to the elevated soluble interleukin-2 receptor and the detection of flower cells in the screening blood test, the high-resolution computed tomography findings, atypical of PCP, were clues to the diagnosis of ATLL. ATLL should be considered as an underlying disease when patients present with PCP, even in non-endemic areas.