Asymmetric Organocatalysis of Activated Alkynes and Enynes. Issue 7 (1st June 2021)

• Record Type: Journal Article
• Authors: Sharma, Akashdeep; Nagaraju, Koppanathi; Rao, Gunda Ananda; Gurubrahamam, Ramani; Chen, Kwunmin
• Is Part Of: Asian journal of organic chemistry. Volume 10:Issue 7(2021)
• Page Start: 1567
• Page End: 1579
• Publication Date: 2021-06-01
• Subjects: Enantioselective -- Organocatalysis -- Alkynes -- Alkynals -- Alkynones -- Alkynoates -- Enynes -- Enynones; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202100252
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: Enantioselective organocatalytic protocols for the functionalization of electron‐deficient internal alkynes and enynes are reviewed. This review focuses on the applicability of activated conjugated π‐systems in asymmetric synthesis for providing diversified chiral entities under metal‐free reaction conditions. Various organocatalytic strategies with different catalytic modes are demonstrated. Abstract : Enantioselective organocatalytic syntheses were developed for the functionalization of electron‐deficient alkynes and enynes. These methods provide diversified chiral entities with different catalytic modes.