CHANGES IN MYOPIC MACULOPATHY BASED ON ATN CLASSIFICATION SYSTEM: An Optical Coherence Tomography Angiography Study. Issue 4 (April 2022)

• Record Type: Journal Article
• Authors: Wang, Yanbing; Jiang, Chengyan; Zhao, Xiujuan; Chen, Jing; Li, Jun; Huang, Xia; Liu, Bingqian; Lu, Lin
• Is Part Of: Retina. Volume 42:Issue 4(2022)
• Page Start: 679
• Page End: 688
• Publication Date: 2022-04
• Subjects: myopic maculopathy -- ATN classification system -- optical coherence tomography angiography; Retina -- Diseases -- Periodicals; Retinal Diseases; Vitreous Body; 617.735
• DOI: 10.1097/IAE.0000000000003397
• Languages: English
• ISSNs: 0275-004X

Abstract

Abstract : Supplemental Digital Content is Available in the Text. Progressive ischemia in the macula may play an important role in the development of myopic atrophic maculopathy. Active choroidal neovascularization may have manifested as compensation for the decrease in macular choroidal thickness and choriocapillaris flow. Abstract : Purpose: To assess changes in myopic maculopathy based on the ATN classification system with optical coherence tomography angiography. Methods: This was a cross-sectional study. The macular choroidal thickness (MCT) and the choriocapillaris flow (CC) were measured with optical coherence tomography angiography. The relationship of MCT and CC with different chorioretinal atrophy (A), myopic foveoschisis (T), and myopic neovascularization (N) grades was investigated. Results: One hundred and fifty-three participates (219 eyes) were included. MCT and CC had no significant correlation with different T grades ( P > 0.05). Choriocapillaris flow had a significant decrease in eyes with lacquer cracks compared with those with no neovascular maculopathy ( P < 0.05) and showed a significant increase in active choroidal neovascularization compared with those with lacquer cracks ( P < 0.05). Macular choroidal thickness and CC had negative correlations with different A grades ( P < 0.001). MCT showed the greatest decrease in the early stage of myopic atrophic maculopathy ( P < 0.001), and CC showed the most significant reduction in the late stage ( P < 0.001). Conclusion: Choroidal changes in the highly myopic patients were detected by optical coherence tomography angiography. Progressive ischemia in the macula may play an important role in the development of myopic atrophic maculopathy. Active choroidal neovascularization may have manifested as compensation for the decrease in MCT and CC. On the contrary, myopic traction maculopathy had little correlation with choroidal changes.