Effects of DNA Immunoadsorption Combined with Medication on Immune Function and Renal Function in Patients with Systemic Lupus Erythematosus. (21st February 2023)

• Record Type: Journal Article
• Authors: Bai, Lijie; Sun, Mingxia; Wu, Guiying; Wang, Jing; Wang, Yong; Shi, Jun; Zhang, Liying
• Other Names: Liu Fenglin Academic Editor.
• Is Part Of: Journal of environmental and public health. Volume 2023(2023)
• Publication Date: 2023-02-21
• Subjects: Environmental health -- Periodicals; Occupational diseases -- Periodicals; Public health -- Periodicals; 613.105
• DOI: 10.1155/2023/2843979
• Languages: English
• ISSNs: 1687-9805

Abstract

Abstract : Objective . At present, glucocorticoids combined with cyclophosphamide are still used for the clinical treatment of systemic lupus erythematosus (SLE). However, long-term practice has shown that drug treatment currently has the phenomena of long treatment duration, uncontrollable conditions in a short period of time, and unsatisfactory efficacy. DNA immunoadsorption therapy is a newly developed therapy. The combination of drugs and DNA immunoadsorption has been reported for the treatment of SLEN in clinics for a long time. In this study, we observed the effects of DNA immunoadsorption combined with drug therapy on immune function and renal function in patients with systemic lupus erythematosus (SLE). The results showed that the DNA immunosorbent assay combined with medication in the treatment of SLE could quickly and specifically remove pathogenic substances from patients, improve renal function, immune function, and complement levels in patients, and help to relieve disease activity.