Low-Grade Hidradenocarcinoma of the Foot With Metastasis to a Lymph Node. (April 2023)

• Record Type: Journal Article
• Authors: Roman, Jorge; Chung, Catherine G.; Sangueza, Martin; Plaza, Jose A.
• Is Part Of: American journal of dermatopathology. Volume 45:Number 4(2023)
• Page Start: 269
• Page End: 272
• Publication Date: 2023-04
• Subjects: hidradenocarcinoma -- atypical hidradenoma -- low-grade hidradenocarcinoma; Skin -- Diseases -- Periodicals; Histology, Pathological -- Periodicals; 616.50705
• DOI: 10.1097/DAD.0000000000002387
• Languages: English
• ISSNs: 0193-1091

Abstract

Abstract: Hidradenocarcinoma (HAC) is a rare adnexal tumor associated with the potential for locoregional recurrence and systemic metastasis. The clinical appearance of HAC is nonspecific, frequently presenting as a solitary firm subcutaneous nodule or plaque on the head and neck region or distal extremities. These tumors show histomorphologic heterogeneity, as they can be low and high grade. Distinguishing HAC from hidradenoma, especially the low-grade variant of HAC, can be challenging as both tumors can show histologic overlapping features. In this article, we describe a case of a 33-year-old patient presenting with a low-grade HAC of the plantar foot who was subsequently found to have lymph node metastasis.