Aerobic cross-dehydrogenative coupling of toluenes and o-phenylenediamines by flavin photocatalysis for the facile synthesis of benzimidazoles. Issue 10 (20th February 2023)

• Record Type: Journal Article
• Authors: Shiogai, Yuta; Oka, Marina; Iida, Hiroki
• Is Part Of: Organic & biomolecular chemistry. Volume 21:Issue 10(2023)
• Page Start: 2081
• Page End: 2085
• Publication Date: 2023-02-20
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d3ob00113j
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An atom-economical synthesis of benzimidazoles was performed by the flavin-photocatalysed aerobic oxidative cross-dehydrogenative coupling of toluenes and o -phenylenediamines. Abstract : Herein, we demonstrate a green atom-economical synthesis of benzimidazoles via the flavin-photocatalysed aerobic oxidative cross-dehydrogenative coupling of toluenes and o -phenylenediamines. The proposed metal-free reaction proceeds in methanol/H2 O under visible light irradiation by consuming only molecular oxygen from atmospheric air and produces only water as waste.