Synthesis of Sulfonylated Pyrrolines and Pyrrolinones via Ag‐mediated Radical Cyclization of Olefinic Enamides with Sodium Sulfinates. Issue 2 (23rd December 2020)

• Record Type: Journal Article
• Authors: Ding, Ran; Mao, Ming‐Hua; Jia, Wei‐Zhen; Fu, Jian‐Ming; Liu, Lei; Mao, Yue‐Yuan; Guo, Yu; Wang, Pei‐Long
• Is Part Of: Asian journal of organic chemistry. Volume 10:Issue 2(2021)
• Page Start: 366
• Page End: 370
• Publication Date: 2020-12-23
• Subjects: sulfonylated pyrrolines -- radical cyclization -- sodium sulfonates -- enamides; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202000664
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: We report a practical method for the radical cyclization of olefinic enamides using sodium sulfinates to produce a series of sulfonylated pyrrolines and pyrrolinones. This strategy features a wide functional group tolerance and provides convenient access to a series of valuable prochiral pyrroline and pyrrolinone building blocks. Abstract : A practical method for the radical cyclization of olefinic enamides using sodium sulfinates to produce a series of sulfonylated pyrrolines and pyrrolinones is reported. This strategy features a wide functional group tolerance and provides convenient access to a series of valuable prochiral pyrroline and pyrrolinone building blocks.