Stereoselective Synthesis of (Z)‐Dihomoallylic Phosphonates with Quaternary Carbon Center by Palladium‐Catalyzed Bisallylation of Vinylethyene Carbonates with β‐Ketophosphonates. Issue 4 (24th February 2021)

• Record Type: Journal Article
• Authors: Liu, Zhigang; Ke, Miaolin; Zhang, Ke; Zuo, Sheng; Jiang, Meifen; Chen, Fener
• Is Part Of: Asian journal of organic chemistry. Volume 10:Issue 4(2021)
• Page Start: 757
• Page End: 761
• Publication Date: 2021-02-24
• Subjects: homoallylic phosphonates -- β-ketophosphonates -- palladium-catalyzed -- quaternary carbon center -- (Z)-stereoselectivity; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202100054
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: A palladium‐catalyzed bisallylation of vinylethylene carbonates with β ‐ketophosphonates to access to ( Z )‐trisubstituted dihomoallylic phosphonates bearing a quaternary carbon center with good regio‐ and stereoselectivity is reported. This operationally simple protocol exhibits excellent functional group tolerance to deliver valuable dihomoallylic phosphonates. Abstract : Palladium‐catalyzed bisallylation of vinylethylene carbonates with β ‐ketophosphonates is reported to access to (Z)‐trisubstituted dihomoallylic phosphonates bearing a quaternary carbon center with good regio‐ and stereoselectivity. This operationally simple protocol exhibits excellent functional group tolerance to deliver valuable dihomoallylic phosphonates.