Real‐time intravascular ultrasound guidance: A novel technique for accurate placement of ostial stents. Issue 3 (16th June 2021)

• Record Type: Journal Article
• Authors: Harding, Scott A.; Webber, Bruce; Fairley, Sarah; Ormiston, John A.
• Is Part Of: Catheterization and cardiovascular interventions. Volume 99:Issue 3(2022)
• Page Start: 699
• Page End: 705
• Publication Date: 2021-06-16
• Subjects: intravascular ultrasound -- ostial -- percutaneous coronary intervention -- stenting; Heart -- Diseases -- Diagnosis -- Periodicals; Cardiac catheterization -- Periodicals; 616.1207572
• DOI: 10.1002/ccd.29830
• Languages: English
• ISSNs: 1522-1946

Abstract

Abstract: Objectives: To describe a novel technique for ostial stent placement using real‐time IVUS guidance. Background: Accurate placement of coronary stents at ostial locations is challenging with the true ostium frequently being missed increasing the risk of adverse events. We have developed a novel technique for ostial stent placement and report our benchtop testing and initial clinical experience. Methods: Benchtop testing was performed to validate the appearance of the stent and delivery system on IVUS. Benchtop testing of real‐time IVUS guided ostial stent positioning was carried out in a left main bifurcation phantom. Real‐time IVUS guidance of stent placement in aorto‐ostial, ostial left anterior descending (LAD), or ostial circumflex lesions was assessed in a prospective registry. Results: Bench model IVUS demonstrated clear differences between the appearances of the stent and other components of the delivery system. Positioning of 10 consecutive stents into the ostial LAD using real‐time IVUS guidance was assessed in a left main bifurcation model. Median distance from proximal stent edge to LAD ostium was 0.39 mm (interquartile range 0.31 to 0.73). Real‐time IVUS guidance of ostial stent placement was performed in 50 patients (51 lesions). Angiographic success was 100%. IVUS post‐stenting demonstrated median distance from the proximal stent edge to the ostium was 0.2 mm (interquartile range 0.1 to 0.5 mm). There was one periprocedural myocardial infarction but no other major adverse cardiac events at 30‐days. Conclusions: We have developed a novel technique using real‐time IVUS guidance allowing accurate ostial stent placement.