Bilateral recurrent ocular surface squamous cell cancer associated with epidermodysplasia verruciformis. (30th January 2015)

• Record Type: Journal Article
• Authors: Arora, Tarun; Sharma, Sourabh; Sharma, Namrata; Titiyal, Jeewan S
• Is Part Of: BMJ case reports. Volume 2015
• Publication Date: 2015-01-30
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2014-207495
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : A 17-year-old boy, presented with a 2-year history of bilateral, recurrent ocular surface mass. Dermatological evaluation revealed the presence of multiple hypopigmented macules over his body. Skin biopsy showed features typical of epidermodysplasia verruciformis. Topical mitomycin C (0.02%) was administered in both eyes for 6 weeks (three 1-week cycles over 6 weeks). While the mass in the left eye regressed, the mass in the right eye was excised under guidance of intraoperative frozen section. Triple-freeze thaw cryotherapy of the surrounding conjunctiva along with placement of amniotic membrane graft was performed. Postoperative mitomycin C (0.02%) was administered for another 6 weeks (three 1-week cycles over 6 weeks) in both eyes. At 4 years of follow-up, no recurrence has been noted.