A multimodal imaging approach to foreign accent syndrome. A case report. Issue 6 (2nd November 2022)

• Record Type: Journal Article
• Authors: Demichelis, Greta; Duran, Dunja; Ciullo, Giuseppe; Lorusso, Lorenzo; Zago, Stefano; Palermo, Sara; Nigri, Anna; Leonardi, Matilde; Bruzzone, Maria Grazia; Fedeli, Davide
• Is Part Of: Neurocase. Volume 28:Issue 6(2022)
• Page Start: 467
• Page End: 476
• Publication Date: 2022-11-02
• Subjects: Foreign accent syndrome -- fMRI -- DTI -- resting-state fMRI -- MEG; Neurology -- Periodicals; Neuropsychology -- Case Report; Mental Disorders -- Case Report; Nervous System Diseases -- Case Report; 616.8
• DOI: 10.1080/13554794.2023.2168558
• Languages: English
• ISSNs: 1355-4794

Abstract

ABSTRACT: This article describes a case of Foreign accent syndrome (FAS) in an Italian woman who developed a Canadian-like foreign accent without brain damage (functional FAS). The patient underwent an in-depth neuroimaging and (neuro)psychological evaluation. Language networks in the frontotemporal-parietal areas were typically activated bilaterally through fMRI and MEG assessments based on task-based data. Resting-state fMRI showed preserved connectivity between language areas. An obsessive-compulsive personality profile and mild anxiety were found, suggesting psychological and psychiatric factors may be relevant. Accordingly with our findings, multimodal imaging is beneficial to understand FAS neurological and functional etiologies.