After 2 years of the COVID-19 pandemic, translating One Health into action is urgent. Issue 10378 (4th March 2023) - Lefrançois, Thierry; Malvy, Denis; Atlani-Duault, Laetitia; Benamouzig, Daniel; Druais, Pierre-Louis; Yazdanpanah, Yazdan; Delfraissy, Jean-François; Lina, Bruno