A Normative Brain MRI Database of Neurotypical Participants from 5 to 90 Years of Age. (3rd March 2023)

• Record Type: Journal Article
• Authors: Treit, Sarah; Rickard, Julia N.; Stolz, Emily; Solar, Kevin; Seres, Peter; Emery, Derek; Beaulieu, Christian
• Is Part Of: Canadian journal of neurological sciences. Volume 50:Number 2(2023)
• Page Start: 282
• Page End: 286
• Publication Date: 2023-03-03
• Subjects: Normative database -- MRI -- Development -- Aging -- Brain; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Electronic journals; 616.8
• DOI: 10.1017/cjn.2021.513
• Languages: English
• ISSNs: 0317-1671

Abstract

ABSTRACT: Brain magnetic resonance imaging (MRI) studies of clinical populations often require comparison to a normative 'control' cohort, usually of similar age/sex, scanned with the same protocol. The goal here was to create a normative brain MRI database of common quantitative methods to be used in comparisons with a variety of neurological disorders across the lifespan. 378 neurotypical controls (aged 5–90 years; median 31 years; 216 females, 162 males) completed brain MRI, cognitive testing, clinical assessment, and a demographics questionnaire. In addition, this large normative sample will yield novel insight into healthy brain development and aging.