New progress with calcium-binding protein S100A16 in digestive system disease. (4th March 2023)

• Record Type: Journal Article
• Authors: Li, Binbin; Zhu, Wanqing; Shi, Di; Che, Huilin; Lyu, Qinglan; Jiang, Bimei
• Is Part Of: Expert review of gastroenterology & hepatology. Volume 17:Number 3(2023)
• Page Start: 263
• Page End: 272
• Publication Date: 2023-03-04
• Subjects: S100A16 -- calcium-binding protein -- colorectal cancer -- pancreatic cancer -- digestive system; Gastroenterology -- Periodicals; Liver -- Diseases -- Periodicals; 616.3
• DOI: 10.1080/17474124.2023.2174968
• Languages: English
• ISSNs: 1747-4124

Abstract

ABSTRACT: Introduction: This review summarizes and analyzes the abnormal expression and mechanism of S100A16 in digestive system diseases, which is expected to provide new ideas and methods for adjuvant treatment and prognosis evaluation of digestive system diseases. Areas covered: Based on original publications found in database systems (PubMed, Cochrane), we introduce the mechanism and research progress of S100A16 in digestive system tumors, inflammatory bowel disease and fatty liver. Expert opinion: S100A16 is closely related to the proliferation, migration, and invasion of digestive system tumor cells. Further, it plays an important role in inflammatory bowel disease and fatty liver.