Exploring the chemical space of phenyl sulfide oxidation by automated optimization. Issue 3 (15th February 2023)

• Record Type: Journal Article
• Authors: Mueller, Pia; Vriza, Aikaterini; Clayton, Adam D.; May, Oliver S.; Govan, Norman; Notman, Stuart; Ley, Steven V.; Chamberlain, Thomas W.; Bourne, Richard A.
• Is Part Of: Reaction chemistry & engineering. Volume 8:Issue 3(2023)
• Page Start: 538
• Page End: 542
• Publication Date: 2023-02-15
• Subjects: Reaction mechanisms (Chemistry) -- Periodicals; Chemical engineering -- Periodicals; Chemical engineering; Reaction mechanisms (Chemistry); Periodicals; 547.705
• DOI: 10.1039/d2re00552b
• Languages: English
• ISSNs: 2058-9883

Abstract

Abstract : Automated platforms allow for rapid, detailed screening of chemical systems. Abstract : Automated platforms allow for fast and efficient optimisation of single and multi-objective chemical systems. Herein, we report the application of automated optimisation platforms for the chemical screening of sulfide oxidations in flow. The identification of different optima for each substrate highlights the requirement of rapid, individual experimental optimisation for successful compound screening.