Case report: a transcatheter aortic valve replacement failure secondary to COVID-19 infection. Issue 2 (31st January 2023)

• Record Type: Journal Article
• Authors: Tacon, P Ryan; Cao, Louie; Birkeland, Kade; Kedan, Ilan
• Editors: Shaheen, Sameh; Stathogiannis, Konstantinos; Regazzoli-Lancini, Damiano; Hashem, Anas Mohamad; van Trier, Tinka Julia
• Is Part Of: European heart journal. Volume 7:Issue 2(2023)
• Publication Date: 2023-01-31
• Subjects: Case report -- Prosthetic valve thrombosis -- Aortic valve -- Valve replacement -- Acute heart failure -- Thrombosis -- Pulmonary oedema; Cardiology -- Periodicals; Cardiology -- Case studies -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Diseases -- Case studies -- Periodicals; 616.12
• DOI: 10.1093/ehjcr/ytad054
• Languages: English
• ISSNs: 2514-2119

Abstract

Abstract: Background: Valve thrombosis is a well-documented cause of bioprosthetic valve failure. Case reports have been published of prosthetic valve thrombosis secondary to COVID-19 infection. This is the first case report of COVID-19 associated valve thrombosis in a patient with transcatheter aortic valve replacement (TAVR). Case summary: A 90-year-old female with atrial fibrillation on therapeutic apixaban and status-post TAVR presented with COVID-19 infection and was found to have severe bioprosthetic valvular regurgitation with features suggestive of valve thrombosis. She underwent valve-in-valve TAVR with resolution of valvular dysfunction. Discussion: This case report contributes to a growing body of evidence describing the occurrence of thrombotic complications in patients with valve replacement and COVID-19 infection. Increased vigilance and continued investigation are warranted to better characterize thrombotic risk and to inform optimal antithrombotic strategies during COVID-19 infection.