Partly-O-Diamond Solution-Gate Field-Effect Transistor as an Efficient Biosensor of Glucose. Issue 3 (9th March 2023)

• Record Type: Journal Article
• Authors: Zhang, Qianwen; Du, Yuxiang; Chang, Xiaohui; Xu, Bangqiang; Chen, Genqiang; He, Shi; Dan Zhang, ; Li, Qi; Wang, Juan; Wang, Ruozheng; Wang, Hong-Xing
• Is Part Of: Journal of the Electrochemical Society. Volume 170:Issue 3(2023)
• Publication Date: 2023-03-09
• Subjects: Electrochemistry -- Periodicals; 541.3705
• DOI: 10.1149/1945-7111/aca8d4
• Languages: English
• ISSNs: 0013-4651

Abstract

Abstract : Assessment of glucose concentration is vital for diagnosis and treatment of diabetes mellitus. Since the electrochemical advantages of diamond for biosensing, we introduced partly-oxygen-diamond solution-gate field-effect transistor (SGFET) to detect glucose. Partly-O-diamond was obtained from H-diamond by ultraviolet ozone treatment. Then, 1-pyrenebutyric acid–N-hydroxy succinimide ester and glucose oxidase were modified on diamond surface. At last, shifts of transfer characteristics were applied to determine glucose concentration. The as-prepared biosensor exhibited a wide linear response from 10 −5 to 10 −1 M with high sensitivity of −53 mV/log10 [glucose concentration]. Furthermore, this biosensor showed good repeatability and stability in multiple detections.