Comparison of Blood (1–>3)-β-d-Glucan Levels in AIDS-Related Pneumocystis jirovecii Pneumonia and AIDS-Related Progressive Disseminated Histoplasmosis. (31st March 2021)

• Record Type: Journal Article
• Authors: Saccente, Michael; Krishnan, Gayathri
• Is Part Of: Clinical infectious diseases. Volume 73:Number 6(2021)
• Page Start: 1100
• Page End: 1102
• Publication Date: 2021-03-31
• Subjects: (1–>3)-β-D-glucan -- disseminated histoplasmosis -- Pneumocystis jirovecii -- AIDS; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciab277
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: In this retrospective study, (1–>3)-β-d -glucan (B-glucan) was an unreliable marker for AIDS-related Pneumocystis jirovecii pneumonia (PCP) because a high percentage of participants with progressive disseminated histoplasmosis and respiratory symptoms had a positive B-glucan result. Where histoplasmosis is common, attributing B-glucan positivity to PCP without further testing risks misdiagnosis.