Diagnostic Performance of 0.55 T MRI for Intracranial Aneurysm Detection. Issue 2 (2nd February 2023)

• Record Type: Journal Article
• Authors: Osmanodja, Filiz; Rösch, Julie; Knott, Michael; Doerfler, Arnd; Grodzki, David; Uder, Michael; Heiss, Rafael
• Is Part Of: Investigative radiology. Volume 58:Issue 2(2023)
• Page Start: 121
• Page End: 125
• Publication Date: 2023-02-02
• Subjects: magnetic resonance angiography -- TOF-MRA -- 0.55 T MRI -- intracranial aneurysms; Diagnosis, Radioscopic -- Periodicals; Radiology, Medical -- Periodicals; 616.0757
• DOI: 10.1097/RLI.0000000000000918
• Languages: English
• ISSNs: 0020-9996

Abstract

Abstract : Objectives: Intracranial aneurysm (IA) is the main cause of subarachnoid hemorrhages. Time-of-flight (TOF) magnetic resonance angiography (MRA) at 1.5 T or 3 T magnetic resonance imaging (MRI) is a well-established method for the diagnosis of IA. The aim of this prospective study was to evaluate the performance of a modern 0.55 T MRI in the diagnosis of IAs in comparison to digital subtraction angiography (DSA) as a standard of reference. Materials and Methods: Seventeen patients with suspicion of single or multiple IAs underwent TOF MRA at 0.55 T MRI 1 day before DSA. Two neuroradiologists independently measured the aneurysm neck, width, and height on 0.55 T, 1.5 T, and 3 T 3D-TOF MRA source images and 2D/3D rotational angiography. The main analysis assessed the intermodality agreement between 0.55 T TOF MRA and DSA using Bland-Altman plots, a Wilcoxon test, and the intraclass correlation coefficient (ICC). In a secondary analysis, aneurysm dimensions were compared between 0.55 T TOF MRA and 1.5/3 T TOF MRA. Interreader agreement was evaluated by ICC. A third neuroradiologist blinded to patient history screened 0.55 T TOF MRA data sets of the aforementioned 17 patients and 15 additional healthy patients for the presence and location of aneurysms. Results: A total of 19 aneurysms in 16 patients were identified in both 0.55 T MRA and DSA. Measurements of the 2 nonblinded readers showed no significant differences between 0.55 T TOF MRA and DSA in the overall aneurysm size (calculated as the mean from height/width/neck) ( P = 0.178), as well as in the mean width ( P = 0.778) and neck values ( P = 0.190). The mean height was significantly larger in 0.55 T TOF MRA in comparison to DSA ( P = 0.020). Intermodality (1.5/3 T TOF MRA) and interrater agreement were excellent (ICC > 0.94). Of the 32 data sets of patients with and without IA, the blinded reader detected all aneurysms correctly by using 0.55 T images. Conclusions: TOF-MRA acquired with a modern 0.55 T MRI is a reliable tool for the detection and initial assessment of IAs.