A model for the catalytic activity of microtubule polymerases. Issue 1 (7th November 2022)
- Record Type:
- Journal Article
- Title:
- A model for the catalytic activity of microtubule polymerases. Issue 1 (7th November 2022)
- Main Title:
- A model for the catalytic activity of microtubule polymerases
- Authors:
- Xie, Ping
- Abstract:
- Abstract: A XMAP215/Stu2/Alp14 polymerase can catalyze processively the tubulin addition to the microtubule (MT) plus end. In this work, a model is proposed for the underlying molecular mechanism of the polymerase activity, where the polymerase can not only catalyze processively the tubulin addition to but also promote the tubulin removal from the MT plus end. Based on the model the dynamics of both the wild‐type and mutant polymerases is studied theoretically, explaining consistently and well various available experimental data. To further test the model, predicted results are provided.
- Is Part Of:
- Cytoskeleton. Volume 80:Issue 1/2(2023)
- Journal:
- Cytoskeleton
- Issue:
- Volume 80:Issue 1/2(2023)
- Issue Display:
- Volume 80, Issue 1 (2023)
- Year:
- 2023
- Volume:
- 80
- Issue:
- 1
- Issue Sort Value:
- 2023-0080-0001-0000
- Page Start:
- 7
- Page End:
- 20
- Publication Date:
- 2022-11-07
- Subjects:
- microtubule depolymerization -- microtubule polymerization -- molecular motor
Cytoskeleton -- Periodicals
571.65405 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1949-3592 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/cm.21734 ↗
- Languages:
- English
- ISSNs:
- 1949-3584
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3506.857500
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 26017.xml